Crystal chemistry and dissolution of calcium phosphate in dental enamel
Crystal chemistry and dissolution of calcium phosphate in dental enamel
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DOI：
10.1180/002646199548934
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发表时间：
1999-12-01
影响因子：
2.7
通讯作者：
Gao, XJ
中科院分区：
文献类型：
--
作者：
Dowker, SEP;Anderson, P;Gao, XJ
矿物组分（至少95wt. %）的牙釉质是具有多个取代的羟基磷灰石（羟基磷灰石）。釉质的生物起源反映在晶体的不寻常的带状形态中，晶体在c轴方向上极其细长，并且它们在组织内有组织地排列。牙釉质溶解的研究是由非常高的龋齿患病率驱动的。在釉质龋中，最初的脱矿作用导致表面下的矿物质溶解。当表面保持完整时，通过再矿化可以逆转病变。理解釉质脱矿的物理化学过程的问题包括关于在水介质中形成的磷灰石的结构和化学的一般问题。除此之外，还有在不均匀多孔介质中溶解的一般问题，以及釉质磷灰石具有在脱矿过程中变化的天然可变组成的复杂性。模型系统在龋齿研究中的使用说明参照X射线吸收研究的釉质和合成类似物。
The mineral component (at least 95 wt. %) of dental enamel is hydroxyapatite (hydroxylapatite) with multiple substitutions. The biogenic origin of enamel is reflected in the unusual ribbon-like morphology of the crystals, which are extremely elongated in the c-axis direction, and their organized arrangement within the tissue. The study of enamel dissolution has been driven by the very high prevalence of dental caries. In enamel caries, the initial demineralization results in subsurface dissolution of mineral. While the surface remains intact, reversal of the lesion by remineralization is possible. Problems of understanding the physico-chemical processes in enamel demineralization include the general problems concerning the structure and chemistry of apatites formed in aqueous media. Added to these are the general problem of dissolution in an inhomogeneous porous medium and the complication that enamel apatite has a naturally variable composition which changes during dernineralization. The use of model systems in caries research is illustrated by reference to X-ray absorption studies of enamel and synthetic analogues.