A NEW CATHETER SYSTEM FOR CORONARY ANGIOPLASTY
A NEW CATHETER SYSTEM FOR CORONARY ANGIOPLASTY
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DOI：
10.1016/0002-9149(82)90047-9
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发表时间：
1982-01-01
影响因子：
2.8
通讯作者：
HARRISON, DC
中科院分区：
文献类型：
--
作者：
SIMPSON, JB;BAIM, DS;HARRISON, DC
一种新的导管系统被设计用于经皮腔内冠状动脉成形术。球囊扩张导管内的独立可移动、末端灵活的导丝有助于选择相关血管。该导丝可以缓慢而小心地穿过冠状动脉狭窄，从而允许球囊导管安全前进。经过动物和尸体心脏测试后，该系统被用于 53 名患有单血管冠状动脉疾病的患者（56 处狭窄），总体初次成功率为 64%。在这 56 例中的最后 41 例中，使用缩小直径的球囊导管将成功率提高到 73%。对于冠状动脉左前降支病变的患者，成功率为 89%。 53 名患者中有 3 名（6%）在冠状动脉扩张期间出现并发症，需要进行紧急冠状动脉旁路移植手术。没有发生手术相关死亡或晚期心源性死亡。在平均 8 个月的随访期间（范围 1 至 21），有 1 例晚期死亡（非心脏原因），并且没有晚期心肌梗死。 36 名扩张成功的患者中，有 31 名患者的临床状况持续改善。其余 5 名患者在血管成形术部位出现再狭窄，并在扩张后 3 个月内出现心绞痛复发。其中两名患者接受了重复冠状动脉成形术并恢复了无症状状态，三名患者接受了选择性冠状动脉搭桥手术。
A new catheter system has been designed for percutaneous transluminal coronary angioplasty. An independently movable, flexible-tipped guide wire within the balloon dilation catheter facilitates selection of the involved vessel. This guide wire can be passed slowly and carefully beyond the coronary stenosis, permitting safe advancement of the balloon catheter. After testing in animal and cadaver hearts, this system was used in 53 patients (56 stenoses) with single vessel coronary artery disease, with an overall primary success rate of 64 percent. In the last 41 of these 56 cases, use of a balloon catheter with a smaller deflated diameter increased the success rate to 73 percent. In patients with lesions of the left anterior descending coronary artery, the success rate was 89 percent. Three (6 percent) of the 53 patients had complications during coronary arterial dilation that necessitated emergency coronary arterial bypass graft surgery. There were no procedure-related or late cardiac deaths. During the mean follow-up period of 8 months (range 1 to 21), there were one late death (of noncardiac causes) and no late myocardial infarctions. Clinical status was persistently improved in 31 of the 36 patients who had successful dilation. The remaining five patients experienced restenosis at the angioplasty site and return of angina pectoris within 3 months of dilation. Two of these patients had repeat coronary angioplasty with restoration of asymptomatic status, and three had elective coronary bypass graft surgery.