ANTIOXIDANT ACTIVITY OF MELISSA OFFICINALIS LEAVES

ANTIOXIDANT ACTIVITY OF MELISSA OFFICINALIS LEAVES
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香蜂草叶的抗氧化活性

DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
E. Bursal
E. Bursal
中科院分区：
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文献类型：
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作者：
Ekrem Köksal;E. Bursal

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本研究的目的是比较评估蜜蜂花（Melissa officinalis）水提取物（WEM）和乙醇提取物（EEM）的抗氧化活性。通过DPPH和DMPD两种检测方法对WEM和EEM的自由基清除活性进行了评估。WEM能有效清除自由基，对DPPH自由基的半数抑制浓度（IC₅₀）值为31.4微克/毫升，对DMPD阳离子自由基的IC₅₀值为60.5微克/毫升。同样，EEM也能有效清除自由基，对DPPH自由基的IC₅₀值为202.7微克/毫升，对DMPD阳离子自由基的IC₅₀值为120.9微克/毫升。此外，通过铁氰化钾还原法（FRAP）和铜离子还原能力法（CUPRAC）发现，WEM的总还原能力高于EEM。本研究表明，与EEM相比，WEM具有更有效的抗氧化和自由基清除活性。 关键词：抗氧化活性；蜜蜂花；还原能力；自由基清除
The purpose of this study was to evaluate antioxidant activities of water extract of Melissa officinalis (WEM) and ethanol extract of M. officinalis (EEM), comparatively. The WEM and EEM were evaluated for their radical scavenging activities by means of the DPPH and DMPD assays. WEM scavenged radicals effectively with IC50 values of 31.4 µg/mL for DPPH free radical and 60.5 µg /mL for DMPD cation radical. Similarly, EEM scavenged radicals effectively with IC50 values of 202.7 µg/mL for DPPH free radical and 120.9 µg/mL for DMPD cation radical. Also, total reducing power of WEM was found higher than EEM with both potassium ferricyanide reduction (FRAP) and cupric ions reduction capacity methods (CUPRAC). The present study showed that WEM have effective antioxidant and radical scavenging activities as compared to EEM.   Key words: Antioxidant activity, Melissa officinalis, reducing power, radical scavenging.