Comparative structural aspects of cation binding to phosphatidylserine bilayers.
Comparative structural aspects of cation binding to phosphatidylserine bilayers.
复制标题
阳离子与磷脂酰丝氨酸双层结合的比较结构方面。
DOI：
10.1016/0005-2736(85)90251-2
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Shipley,GG
中科院分区：
文献类型：
--
作者：
Hauser,H;Shipley,GG
一系列不同链长的磷脂酰丝氨酸(PS)的一价和二价阳离子络合物的X射线衍射数据显示了一个简单的结构模式。只观察到两种不同碳链倾斜但具有相似极性基团构象的双层结构类型：(I)无水酸性PS，(Ii)无水K+-PS和(Iii)Li+、Mg2+、Ca2+、Sr2+、Ba2+和Pr3+的“水合”PS络合物。X-射线衍射数据表明，PS与Li+、Mg~(2+)、Ca~(2+)等二价阳离子配位后脱水，呈链状(I型)或倾斜(II型)双层结构。
X-ray diffraction data recorded for monovalent and divalent cation complexes of a series of phosphatidylserines (PS) varying in chain length reveal a simple structural pattern. Only two bilayer structural types differing in hydrocarbon chain tilt but with similar polar group conformations are observed for (i) anhydrous acidic PS, (ii) anhydrous K+-PS, and (iii) Li+, Mg2+, Ca2+, Sr2+, Ba2+, and Pr3+complexes of “hydrated” PS. The X-ray diffraction data suggest that PS becomes dehydrated on complexing with Li+, Mg2+, Ca2+, and other divalent cations and adopts either the chain untilted (form I) or tilted (form II) bilayer structure.