Endogenous morphine.
Endogenous morphine.
复制标题
内源性吗啡。
DOI：
10.1016/s1043-6618(95)80003-4
复制
发表时间：
1995
影响因子：
9.3
通讯作者：
Z. Fürst
中科院分区：
文献类型：
--
作者：
S. Hosztafi;Z. Fürst
本文综述了哺乳动物内源性生物碱的发现。吗啡在哺乳动物大脑中的形成是在1970年假设的。用放射免疫法证明吗啡的存在。吗啡的鉴定是通过光谱方法进行的。哺乳动物吗啡的分离提出了生物合成的问题。最近，已经表明生物合成途径与罂粟中存在的生物合成途径相似。
This review surveys the discovery of endogenous alkaloids in mammals. The formation of morphine in mammalian brain was assumed in 1970. The existence of morphine was demonstrated by radioimmunoassay. Identification of morphine was performed by spectroscopic methods. The isolation of mammalian morphine raises the question of biosynthesis. Recently, it has been shown that the biosynthetic pathway is similar to that that exists in poppy.