Videotaped cue for urge to drink alcohol

Videotaped cue for urge to drink alcohol
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DOI:
10.1111/j.1530-0277.2002.tb02584.x
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发表时间:
2002-05-01
影响因子:
3.2
通讯作者:
Renshaw, PF
Renshaw, PF
中科院分区:
医学3区
文献类型:
--
作者:
Streeter, CC;Gulliver, SB;Renshaw, PF

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背景:饮酒的冲动可以通过实际接触一个人喜欢的酒精饮料而强烈而可靠地诱发。不幸的是,这些曝光范例是笨拙的功能磁共振成像研究。本研究的目的是检验观看个性化的录像提示是否会引起酒精渴望。以下假设进行了测试:(1)个性化的线索录像带可以可靠地引起冲动饮酒酒精依赖的参与者和(2)饮酒史可以预测反应cue.Methods:DSM-IV标准被用来确定一个酒精依赖组(ADG)。对照组包括轻度饮酒组和中度饮酒组。在基线和五种体内暴露条件(水(W)、酒精1(A1)、情绪诱导(M)、酒精2(A2)和放松(R))中的每一种条件后评估饮酒的冲动。整个暴露过程都被录了下来。每个参与者的视频片段都经过数字编辑,以产生17.5分钟的提示,并在24至72小时后呈现给参与者。在五个曝光条件下的饮酒冲动的评级进行了比较,无论是在体内和视频曝光sessions.Results:14名参与者(5在轻度饮酒组,4在中度饮酒组,5在ADG)完成了两个会议。每组的参与者在体内提示会话(p <0.002)和录像会话(p <0.02)中显示出中性提示暴露(W和R)和酒精相关提示暴露(A1,M和A2)之间的差异。事后比较酒精相关的线索组之间建立,在这两个会议(P(在)(体内)= 0.04; P(录像带)= 0.04),ADG表现出最大的冲动drink.Conclusions:酒精提示反应可以可靠地诱导和评估酒精依赖的参与者通过个性化的录像带。饮酒史与线索反应程度呈正相关。这项研究提高了我们在没有酒精的情况下评估酒精提示反应的能力。
Background: The urge to drink alcohol can be robustly and reliably induced via actual exposure to a person's preferred alcoholic beverage. Unfortunately, these exposure paradigms are unwieldy for functional magnetic resonance imaging studies. The goal of this study was to examine whether viewing a personalized videotaped cue could induce alcohol craving. The following hypotheses were tested: (1) individualized cue videotapes can reliably elicit the urge to drink alcohol in alcohol-dependent participants and (2) alcohol drinking histories can predict reactivity to cue.Methods: DSM-IV criteria were used to identify an alcohol-dependent group (ADG). Controls included a light-drinking group and a moderate-drinking group. Urge to drink alcohol was assessed at baseline and after each of five in vivo exposure conditions: water (W), alcohol 1 (A1), mood induction (M), alcohol 2 (A2), and relaxation (R). The entire exposure session was videotaped. Each participant's video footage was digitally edited to produce a 17.5-min cue that was presented to the participant 24 to 72 hr later. Ratings of urge to drink alcohol across the five exposure conditions were compared for both the in vivo and the video exposure sessions.Results: Fourteen participants (five in the light-drinking group, four in the moderate-drinking group, and five in the ADG) completed both sessions. Participants in each group showed differences between neutral cue exposure (W and R) and alcohol-related cue exposure (A1, M, and A2) in both the in vivo cue session (p < 0.002) and the videotape session (p < 0.02). Post hoc comparisons among the groups to alcohol-related cues established that, in both sessions (p(in) (vivo) = 0.04; p(videotape) = 0.04), the ADG demonstrated the greatest urge to drink.Conclusions: Alcohol cue reactivity can be reliably induced and assessed in alcohol-dependent participants via personalized videotapes. History of alcohol consumption is positively correlated with the degree of cue reactivity. This study advances our ability to assess alcohol cue reactivity in the absence of alcohol.