MELANOCYTIC NEVI IN CHILDREN .1. ANATOMIC SITES AND DEMOGRAPHIC AND HOST FACTORS

MELANOCYTIC NEVI IN CHILDREN .1. ANATOMIC SITES AND DEMOGRAPHIC AND HOST FACTORS
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DOI:
10.1093/oxfordjournals.aje.a117011
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发表时间:
1994-02-15
影响因子:
5
通讯作者:
ARMSTRONG, BK
ARMSTRONG, BK
中科院分区:
医学2区
文献类型:
--
作者:
ENGLISH, DR;ARMSTRONG, BK

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1985年,在西澳大利亚州的珀斯的学童中进行了一项良性黑色素细胞痣的调查,目的是描述痣的患病率和病因。儿童是从珀斯公立学校招募的,这些学校被选为代表人口的社会经济和地理分布。在4,898名符合条件的儿童中,2,595名(53%)的所有痣都由五名护士组成的团队中的一名成员计数。分析仅限于2,552名5-14岁的儿童。欧洲血统的儿童(即,白色儿童)占样本的大多数(2,376名儿童),比其他种族出身的儿童患痣的人数要多得多。在白色儿童中,痣的患病率随着年龄的增长而逐渐增加,尽管每单位皮肤面积的痣数量在9岁左右达到一个平台。男孩在所有年龄段都比女孩有更多的痣。每单位面积的痣数在上肢和面颈部的侧面最高,在下肢最低。父母出生在南欧的孩子很可能很少有痣。红头发的儿童痣相对较少,但浅色皮肤的儿童痣通常比深色皮肤的儿童多。晒黑的能力和烧伤的倾向也与痣的数量有关,尽管不是以简单的方式;痣的数量在这两个变量的中间类别中最高。与雀斑的关系也很复杂;痣的平均数量随着雀斑的增加而增加,直到雀斑变得中度到重度,之后它下降。
A survey of benign melanocytic nevi was conducted among schoolchildren in Perth, Western Australia, in 1985, with the aim of describing the prevalence and causes of nevi. Children were recruited from Perth public schools that were chosen to be representative of the socioeconomic and geographic distribution of the population. Of 4,898 eligible children, 2,595 (53%) had all of their nevi counted by one member of a team of five nurses. Analysis was restricted to 2,552 children aged 5-14 years. Children of European origin (i.e., white children), who comprised the majority of the sample (2,376 children), had many more nevi than did children of other ethnic origins. Among white children, the prevalence of nevi increased progressively with age, although the number of nevi per unit of skin area reached a plateau at about 9 years of age. Boys had more nevi at all ages than did girls. The number of nevi per unit of area was highest on the lateral surfaces;of the upper limbs and the face and neck, and was lowest on the lower limbs. Children whose parents had been born in Southern Europe were likely to have few nevi. Children with red hair had relatively few nevi, but children with light skin generally had more nevi than children with darker skin. Ability to tan and propensity to burn were also associated with number of nevi, although not in a simple fashion; numbers of nevi were highest in intermediate categories of these two variables. The relation with freckling was also complex; the mean number of nevi increased with increasing freckling until the freckling became moderate to heavy, after which it fell.