Responses of neurons in macaque MT to unikinetic plaids.
Responses of neurons in macaque MT to unikinetic plaids.
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猕猴 MT 神经元对单动力格子的反应。
DOI：
10.1152/jn.00486.2019
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发表时间：
2019
影响因子：
2.5
通讯作者：
Movshon,JAnthony
中科院分区：
文献类型：
--
作者：
Wallisch,Pascal;Movshon,JAnthony
MT神经元的反应特性通常是用“双动力”格状刺激来研究的，这种刺激由两个沿不同方向移动的正弦波栅叠加而成。使用“单动格子”的眼球运动研究表明，两个重叠的格子中只有一个移动，表明眼睛首先反射性地沿着移动的格子的方向移动，然后才会聚在移动图案的感知方向上。MT被认为是驱动这些反应的视觉信号源。我们想知道，当单独呈现时对MT细胞几乎没有影响的静止栅会在与移动的栅配对时是否会影响MT的响应。我们记录了MT区神经元的细胞外反应，并测量了对静止和移动的格栅以及它们的总和的反应：双动格子和单动格子。正如预期的那样，单独呈现的固定栅格对MT神经元的活动的影响非常小。对移动格子和双动格子的反应与以前报道的相似，表明细胞对格子图案及其组成部分(图案和组成细胞)的运动具有选择性。当用单动格子探测这些神经元时，图案细胞改变了它们的方向偏好，揭示了静态格栅的影响。成分细胞偏好变化很小，或者根本没有变化。这些结果支持这样的观点，即MT区的模式选择性神经元整合了速度差异很大的成分运动，并且它们以一种与约束相交模型一致的方式做到这一点。NEW&NOTEWORTHY人类对移动栅格的感知和眼睛运动反应受到增加第二个静态栅格以创建一种“单动”格子的影响。MT中的细胞对静态栅格没有响应，但这些栅格仍然影响某些MT细胞的方向选择性。受静态栅格影响的细胞是那些针对全局模式的运动进行调谐的细胞，而不是那些仅针对运动目标的个别组件进行调谐的细胞。
Response properties of MT neurons are often studied with “bikinetic” plaid stimuli, which consist of two superimposed sine wave gratings moving in different directions. Oculomotor studies using “unikinetic plaids” in which only one of the two superimposed gratings moves suggest that the eyes first move reflexively in the direction of the moving grating and only later converge on the perceived direction of the moving pattern. MT has been implicated as the source of visual signals that drives these responses. We wanted to know whether stationary gratings, which have little effect on MT cells when presented alone, would influence MT responses when paired with a moving grating. We recorded extracellularly from neurons in area MT and measured responses to stationary and moving gratings, and to their sums: bikinetic and unikinetic plaids. As expected, stationary gratings presented alone had a very modest influence on the activity of MT neurons. Responses to moving gratings and bikinetic plaids were similar to those previously reported and revealed cells selective for the motion of plaid patterns and of their components (pattern and component cells). When these neurons were probed with unikinetic plaids, pattern cells shifted their direction preferences in a way that revealed the influence of the static grating. Component cell preferences shifted little or not at all. These results support the notion that pattern-selective neurons in area MT integrate component motions that differ widely in speed, and that they do so in a way that is consistent with an intersection-of-constraints model.NEW & NOTEWORTHYHuman perceptual and eye movement responses to moving gratings are influenced by adding a second, static grating to create a “unikinetic” plaid. Cells in MT do not respond to static gratings, but those gratings still influence the direction selectivity of some MT cells. The cells influenced by static gratings are those tuned for the motion of global patterns, but not those tuned only for the individual components of moving targets.
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影响因子：
2.5
作者：
Cavanaugh, JR;Bair, W;Movshon, JA
通讯作者：
Movshon, JA
DOI：
10.1523/jneurosci.4387-03.2004
发表时间：
2004-03
期刊：
The Journal of Neuroscience
影响因子：
--
作者：
Christopher C. Pack;Andrew J. Gartland;R. Born
通讯作者：
Christopher C. Pack;Andrew J. Gartland;R. Born
测试神经尖峰计数固有与观察到的过度分散的几率。
影响因子：
2.5
作者：
Taouali,Wahiba;Benvenuti,Giacomo;Wallisch,Pascal;Chavane,Frédéric;Perrinet,LaurentU
通讯作者：
Perrinet,LaurentU
影响因子：
2.5
作者：
ALBRIGHT, TD
通讯作者：
ALBRIGHT, TD
影响因子：
1.8
作者：
V. Ferrera;H. Wilson
通讯作者：
H. Wilson