Antigen presentation to B cells.
Antigen presentation to B cells.
复制标题
抗原呈递给 B 细胞。
DOI：
10.3410/b2-87
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发表时间：
2010-12-17
期刊：
影响因子：
--
通讯作者：
Batista FD
中科院分区：
文献类型：
--
作者：
Harwood NE;Batista FD
B细胞能够通过产生高亲和力抗体和建立免疫记忆，对一系列令人困惑的潜在致病性抗原产生应答。因此，受调节的B细胞活化对于保护免受各种细菌和病毒感染以及癌症至关重要。在这里，我们讨论了一些最近的影像学研究，提供了新的见解的各种机制，B细胞激活启动在体内淋巴结。
B cells are capable of mounting responses to a bewildering range of potentially pathogenic antigens through the production of high-affinity antibodies and the establishment of immunological memory. Thus, regulated B-cell activation is critical for protection against a variety of bacterial and viral infections, as well as cancers. Here, we discuss a number of recent imaging studies that have provided new insights into the variety of mechanisms by which B-cell activation is initiated in the lymph node in vivo.