Panax ginseng and its derivatives: Promoting angiogenesis in ischemic diseases - A mechanistic overview
Panax ginseng and its derivatives: Promoting angiogenesis in ischemic diseases - A mechanistic overview
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DOI：
10.1016/j.jff.2023.105762
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发表时间：
2023-09-07
影响因子：
5.6
通讯作者：
Zheng，Zhenzhen
中科院分区：
文献类型：
--
作者：
Song，Xiayinan;Gao，Weihan;Zheng，Zhenzhen
缺血性疾病，包括冠心病和外周动脉阻塞性疾病，在世界范围内构成严重的健康威胁。血管生成疗法已经成为对抗这些疾病的综合方法。近年来，中医药对缺血性疾病的治疗作用日益受到重视，人参（Panax ginseng）是五加科（Araliaceae）人参属（Panax genus）多年生草本植物，广泛应用于缺血性疾病的临床治疗。研究表明人参具有促进血管生成的作用。本文对人参及其提取物和成分的促血管生成活性及其机制进行了综述。本文综述了人参与促血管生成的关系，为临床实践提供了新的思路。
Ischemic diseases, including coronary heart disease and peripheral arterial obstructive disease, pose significant health threats worldwide. Angiogenic therapy has emerged as a comprehensive approach to combat these diseases. In recent years, traditional Chinese medicine has attracted increased attention due to its demonstrable therapeutic effects on ischemic diseases.Panax ginseng, a perennial herb from thePanaxgenus of theAraliaceaefamily, is widely employed in the clinical treatment of ischemic conditions. Previous research reveals thatPanax ginsengexhibits potent pro-angiogenic properties. In this review, we present a timely examination of the pro-angiogenic activities and underlying mechanisms ofPanax ginseng, its extracts, and its constituent compounds. Overall, this review offers a comprehensive understanding of the relationship betweenPanax ginsengand pro-angiogenesis, providing novel insights for clinical practice.