Symmetry and the energy landscapes of biomolecules
Symmetry and the energy landscapes of biomolecules
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DOI：
10.1073/pnas.93.25.14249
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发表时间：
1996-12-10
影响因子：
11.1
通讯作者：
Wolynes, PG
中科院分区：
文献类型：
--
作者：
Wolynes, PG
利用能量景观理论讨论了对称性在蛋白质折叠中的作用。分析论证表明，如果结构是对称的，则更容易找到具有能够快速折叠的漏斗能量景观的序列。讨论了幻数小团簇相变的类比。
The role of symmetry in the folding of proteins is discussed using energy landscape theory. An analytical argument shows it is much easier to find sequences with funneled energy landscape capable of fast folding if the structure is symmetric. The analogy with phase transitions of small clusters with magic numbers is discussed.