EVOLVING PITUITARY-HORMONE DEFICIENCY IS ASSOCIATED WITH PITUITARY VASCULOPATHY - DYNAMIC MR STUDY IN CHILDREN WITH HYPOPITUITARISM, DIABETES-INSIPIDUS, AND LANGERHANS CELL HISTIOCYTOSIS
EVOLVING PITUITARY-HORMONE DEFICIENCY IS ASSOCIATED WITH PITUITARY VASCULOPATHY - DYNAMIC MR STUDY IN CHILDREN WITH HYPOPITUITARISM, DIABETES-INSIPIDUS, AND LANGERHANS CELL HISTIOCYTOSIS
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DOI：
10.1148/radiology.193.2.7972767
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发表时间：
1994-11-01
期刊：
影响因子：
19.7
通讯作者：
SEVERI, F
中科院分区：
文献类型：
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作者：
MAGHNIE, M;GENOVESE, E;SEVERI, F
目的：为评估垂体功能减退症患儿的垂体血管化情况，材料与方法：对21例（男11例，女10例，年龄4-17岁）和10例年龄相匹配的对照患者，在注射gadopenteate二聚谷氨酰胺后，通过垂体柄获得动态MR图像。结果：除了4例中央DI和粗柄患者外，所有受试者的垂体后叶与直窦的初始增强同时发生。4例垂体后叶初始增强延迟的患者，整个垂体前叶增强时间明显延长（P < 0.005）。结论：快速分幅动态磁共振成像提供了正常和异常垂体下丘脑区血供的新信息。垂体后叶增强时间超过20秒，垂体前叶增强时间超过30秒，提示垂体下动脉和门静脉系统血管化异常。
PURPOSE: To assess pituitary vascularization in children with hypopituitarism,MATERIALS AND METHODS: Dynamic MR images were obtained through the pituitary stalk after injection of gadopentetate dimeglumine in 21 patients (11 boys and 10 girls, aged 4-17 years) and 10 age-matched control subjects.RESULTS: Initial enhancement of the posterior pituitary lobe occurred simultaneously with that of the straight sinus in all subjects except four patients with central DI and a thick stalk. Enhancement of the entire anterior pituitary lobe was statistically significantly prolonged (P < .005) in the four patients with delayed initial posterior pituitary lobe enhancement.CONCLUSION: Fast-framing dynamic MR imaging provides new information on the blood supply of the hypothalamic pituitary area in normal and abnormal pituitary glands. Enhancement times exceeding 20 seconds for the posterior pituitary lobe and 30 seconds for the anterior pituitary lobe may suggest abnormal vascularization in the hypophyseal arteries and portal system.