Risk factors for coronary heart disease in the Japanese--comparison of the background of patients with acute coronary syndrome in the ASPAC study with data obtained from the general population. Asia-Pacific Collaboration on CHD Risk Factor Intervention study.
Risk factors for coronary heart disease in the Japanese--comparison of the background of patients with acute coronary syndrome in the ASPAC study with data obtained from the general population. Asia-Pacific Collaboration on CHD Risk Factor Intervention study.
复制标题
日本人冠心病的危险因素——ASPAC 研究中急性冠状动脉综合征患者背景与普通人群数据的比较。
DOI：
10.5551/jat.9.191
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发表时间：
2002
影响因子：
4.4
通讯作者：
H. Tenba
中科院分区：
文献类型：
--
作者：
A. Yamamoto;Gemma Richie;H. Nakamura;S. Hosoda;M. Nobuyoshi;M. Matsuzaki;Chee;A. Keech;H. Mabuchi;H. Horibe;H. Tenba
通过比较参加亚太冠心病危险因素干预协作组（ASPAC）研究的急性冠状动脉综合征（ACS）患者中代谢危险因素的患病率与1990年进行的血脂调查结果，并将其与该地区其他国家和地区的ASPAC数据进行比较，评估了日本人冠心病（CHD）代谢危险因素的相对重要性。与其他国家和地区一样，高血压是日本ACS患者中最常见的危险因素。身体质量指数（BMI）为30或以上的肥胖症患病率比一般人群高出数倍，尽管这一比率仍远低于新西兰和新加坡。除高胆固醇血症外，高胆固醇血症和糖尿病也常见于日本ACS患者。当在普通人群中比较有和没有高血压的人之间代谢危险因素的患病率时，最显著的差异是BMI，其次是甘油三酯和总胆固醇。这些结果表明，在日本人群中，高脂血症和糖尿病可能是比LDL-胆固醇更重要的CHD危险因素。
The relative importance of metabolic risk factors for coronary heart disease (CHD) in the Japanese is assessed by comparing their prevalence in patients with acute coronary syndrome (ACS) enrolled in the Asia-Pacific Collaboration on CHD Risk Factor Intervention (ASPAC) study to that obtained by a serum lipid survey carried out in 1990 and also by comparing them to the ASPAC data from other countries and regions in this area. Hypertension was the most prevalent risk factor among Japanese patients with ACS as in the other countries and regions. The prevalence of obesity with a body mass index (BMI) of 30 or more was several times higher than that in the general population, although the rate was still much lower than in New Zealand and Singapore. In addition to hypercholesterolemia, hypertriglyceridemia and diabetes mellitus were frequently found in Japanese patients with ACS. When the prevalence of metabolic risk factors was compared between people with and without hypertension in the general population, the most remarkable difference was seen in BMI, followed by triglyceride and total cholesterol. These results indicate that hypertriglyceridemia and diabetes mellitus may be more important CHD risk factors in the Japanese population than LDL-cholesterol.