Association between the physical activity and heart rate corrected-QT interval in older adults
Association between the physical activity and heart rate corrected-QT interval in older adults
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DOI：
10.1111/ggi.12365
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发表时间：
2015-07-01
影响因子：
3.3
通讯作者：
Kiyonaga, Akira
中科院分区：
文献类型：
--
作者：
Michishita, Ryoma;Fukae, Chika;Kiyonaga, Akira
目的增加身体活动可以降低心血管疾病的发病率和死亡率。相反，心率校正qt （QTc）间期延长与心律失常、心源性猝死和冠状动脉疾病风险增加相关。本横断面研究旨在阐明老年人身体活动水平与QTc间隔之间的关系。方法纳入586例无心血管疾病史且正在服用心血管活性药物的老年人（男性267人，女性319人，年龄71.24.7岁）。采用标准静息12导联心电图仪记录心电图，根据Hodges公式计算QTc间期。使用三轴加速度计评估身体活动水平。参与者被分为四类，这四类被定义为QTc区间的等四分位数分布。结果经年龄、体质指数、腰围、步数等因素调整后，男女QTc间隔时间最长组的不活动时间高于最短组，轻度运动时间显著低于最短组(P
AimIncreased physical activity can reduce the incidence of cardiovascular disease and the mortality rate. In contrast, a prolonged heart rate corrected-QT (QTc) interval is associated with an increased risk of arrhythmias, sudden cardiac death and coronary artery disease. The present cross-sectional study was designed to clarify the association between the physical activity level and the QTc interval in older adults.MethodsThe participants included 586 older adults (267 men and 319 women, age 71.24.7years) without a history of cardiovascular disease, who were taking cardioactive drugs. Electrocardiography was recorded with a standard resting 12-lead electrocardiograph, while the QTc interval was calculated according to Hodges' formula. The physical activity level was assessed using a triaxial accelerometer. The participants were divided into four categories, which were defined equally quartile distributions of the QTc interval.ResultsAfter adjusting for age, body mass index, waist circumference and the number of steps, the time spent in inactivity was higher and the time spent in light physical activity was significantly lower in the longest QTc interval group than in the shortest QTc interval group in both sexes (P