The relationship between crystalline methamphetamine use and methamphetamine dependence
The relationship between crystalline methamphetamine use and methamphetamine dependence
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DOI：
10.1016/j.drugalcdep.2006.04.007
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发表时间：
2006-12-01
影响因子：
4.2
通讯作者：
McLaren, Jennifer
中科院分区：
文献类型：
--
作者：
McKetin, Rebecca;Kelly, Erin;McLaren, Jennifer
背景：本研究的目的是确定结晶甲基苯丙胺使用者是否比使用其他形式药物的人更依赖甲基苯丙胺，如果是，这是否可以通过他们的甲基苯丙胺使用史来解释。方法：采用结构化面对面访谈来评估来自澳大利亚悉尼的 309 名定期甲基苯丙胺使用者的便利样本的药物使用模式和人口统计数据。使用依赖严重程度量表衡量过去一年对甲基苯丙胺的依赖。使用照片识别表确认过去一年使用过结晶甲基苯丙胺。结果：过去一年使用过结晶甲基苯丙胺的参与者比在此期间仅服用其他形式甲基苯丙胺的参与者更有可能对甲基苯丙胺产生依赖性（61％对39％）。甲基苯丙胺依赖还与注射或吸食甲基苯丙胺（分别为 67% 和 58%，鼻内或口服使用甲基苯丙胺分别为 30%）、每周使用甲基苯丙胺超过一周（68% 对 34%）、使用该药物超过 5 年（61% 对 36%）以及在过去一年中使用过“基础”甲基苯丙胺（59% 对 39%）有关。在调整这些甲基苯丙胺使用模式后，结晶甲基苯丙胺的使用仍然与甲基苯丙胺依赖显着相关。结论：过去一年服用结晶甲基苯丙胺的甲基苯丙胺使用者比在此期间未服用结晶形式甲基苯丙胺的甲基苯丙胺使用者更有可能产生依赖。 (c) 2006 Elsevier Ireland Ltd. 保留所有权利。
Background: The aim of the current study was to determine whether crystalline methamphetamine users are more dependent on methamphetamine than people who use other forms of the drug, and if so, whether this could be accounted for by their methamphetamine use history.Method: A structured face-to-face interview was used to assess drug use patterns and demographics among a convenience sample of 309 regular methamphetamine users from Sydney, Australia. Dependence on methamphetamine in the past year was measured using the Severity of Dependence Scale. The use of crystalline methamphetamine in the past year was confirmed using a photographic identification sheet.Results: Participants who had used crystalline methamphetamine in the past year were significantly more likely to be dependent on methamphetamine than participants who took only other forms of methamphetamine during this time (61% versus 39%). Methamphetamine dependence was also associated with injecting or smoking methamphetamine (67% and 58%, respectively versus 30% for intranasal or oral use), using methamphetamine more than weekly (68% versus 34%), having used the drug for more than 5 years (61% versus 36%), and having used 'base' methamphetamine in the past year (59% versus 39%). Crystalline methamphetamine use remained significantly associated with methamphetamine dependence after adjusting for these patterns of methamphetamine use.Conclusions: Methamphetamine users who took crystalline methamphetamine in the past year were more likely to be dependent than methamphetamine users who had not taken the crystalline form of the drug during this time. (c) 2006 Elsevier Ireland Ltd. All rights reserved.