Signet-ring cell carcinoma of the prostate.

Signet-ring cell carcinoma of the prostate.
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前列腺印戒细胞癌。

DOI:
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发表时间:
1992
影响因子:
4.6
通讯作者:
M. Cohen
M. Cohen
中科院分区:
医学2区
文献类型:
--
作者:
K. M. Alline;M. Cohen

文献摘要

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我们报告一个有趣的病例印戒细胞癌的前列腺,即,一种罕见的组织病理模式的前列腺癌。我们报告了本病例的组织学、免疫组织学和电镜检查结果,并将结果与先前报道的病例进行了比较。虽然目前报道的罕见前列腺印戒细胞癌的组织病理表现差异很大,但可以得出以下结论:(1)前列腺印戒细胞癌是一种高级别癌;(2)转移性印戒细胞癌应考虑前列腺原发,特别是当胃肠道检查结果不明确时;(3)粘蛋白、脂质、前列腺特异性抗原、前列腺特异性酸性磷酸酶、癌胚抗原染色变化较大。
We report an intriguing case of signet-ring cell carcinoma of the prostate, ie, a rare histopathologic pattern of prostatic carcinoma. We present the results of histologic, immunohistologic, and electron microscopic examinations in our case, and we compare the findings with those of cases that have been previously reported. Although the histopathologic findings in the rare cases of signet-ring cell carcinoma of the prostate thus far reported have varied greatly, the following conclusions can be made: (1) signet-ring cell carcinoma of the prostate is a high-grade carcinoma; (2) a prostatic primary should be considered in cases of metastatic signet-ring cell carcinoma, especially when results of gastrointestinal studies are unelucidating; and (3) staining for mucin, lipid, prostate-specific antigen, prostate-specific acid phosphatase, and carcinoembryonic antigen is variable.