Detection of West Nile virus sequences in cerebrospinal fluid
Detection of West Nile virus sequences in cerebrospinal fluid
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DOI：
10.1016/s0140-6736(00)02220-0
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发表时间：
2000-05-06
期刊：
影响因子：
168.9
通讯作者：
Lipkin, WI
中科院分区：
文献类型：
--
作者：
Briese, T;Glass, WG;Lipkin, WI
建立了一种灵敏特异的西尼罗病毒实时荧光定量PCR检测方法。对1999年纽约爆发期间获得的标本进行的分析表明，在所有四名死亡患者的脑脊液中都存在病毒序列，而在四名幸存者中只有一人存活。
We have established a sensitive and specific real-time PCR method for detection of West Nile virus. Analysis of specimens obtained during the 1999 New York outbreak indicated the presence of viral sequences in cerebrospinal fluid of all of four individuals with fatal outcomes, and in only one of four who survived.