INFECTIOUS ROUS-SARCOMA VIRUS AND RETICULOENDOTHELIOSIS VIRUS DNAS

INFECTIOUS ROUS-SARCOMA VIRUS AND RETICULOENDOTHELIOSIS VIRUS DNAS
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DOI:
10.1128/jvi.14.5.1132-1141.1974
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发表时间:
1974-01-01
影响因子:
5.4
通讯作者:
TEMIN, HM
TEMIN, HM
中科院分区:
医学2区
文献类型:
--
作者:
COOPER, GM;TEMIN, HM

文献摘要

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描述了一种有效的定量检测传染性劳斯肉瘤病毒和网状内皮组织增生症病毒DNA的方法。病毒DNA的比感染力相当于每105 ~ 106个病毒DNA分子一个感染单位。病毒DNA感染遵循一击动力学。传染性劳斯肉瘤病毒DNA的最小尺寸约为600万道尔顿,而传染性网状内皮组织增生症病毒DNA的最小尺寸更大,为1000万至2000万道尔顿。
An efficient and quantitative assay for infectious Rous sarcoma virus and reticuloendotheliosis virus DNAs is described. The specific infectivities of viral DNA corresponded to one infectious unit per 105to 106viral DNA molecules. Infection with viral DNA followed one-hit kinetics. The minimal size of infectious Rous sarcoma virus DNA was approximately 6 million daltons, whereas the minimal size of infectious reticuloendotheliosis virus DNA was larger, 10 to 20 million daltons.