AN EPIDEMIC OF PRECOCIOUS DEVELOPMENT IN PUERTO-RICAN CHILDREN
AN EPIDEMIC OF PRECOCIOUS DEVELOPMENT IN PUERTO-RICAN CHILDREN
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DOI：
10.1016/s0022-3476(85)80513-8
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发表时间：
1985-01-01
影响因子：
5.1
通讯作者：
DEBORREGO, LC
中科院分区：
文献类型：
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作者：
DERODRIGUEZ, CAS;BONGIOVANNI, AM;DEBORREGO, LC
在过去7年中，波多黎各报告了性发育过早的惊人发生率。全岛男孩乳房早长、阴毛早长、青春期前乳房增大和女孩假性青春期早熟的现象显著增加。几个食品样品分析色谱和胞质受体检测显示，在一些肉类样品中的雌二醇当量显着水平。我们怀疑早期性发育是由儿童及其母亲摄入的食物中的外源性雌激素污染引起的。
An alarming incidence of premature sexual development has been reported in Puerto Rico during the last 7 years. A significant increment of premature thelarche, premature pubarche, prepubertal breast enlargement in boys, and precocious pseudopuberty in girls has been observed throughout the island. Several food specimens analyzed by chromatography and cytosol receptor assay revealed significant levels of estradiol equivalent in some meat samples. We suspect that the early sexual development is caused by exogenous estrogen contamination in the food ingested by the children and by their mothers.