L- and M-cone isolating ERGs: LED versus CRT stimulation
L- and M-cone isolating ERGs: LED versus CRT stimulation
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DOI：
10.1017/s095252380808036x
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发表时间：
2008-05-01
影响因子：
1.9
通讯作者：
Parry, N. R. A.
中科院分区：
文献类型：
--
作者：
Murray, I. J.;Kremers, J.;Parry, N. R. A.
使用双沉默替代，可以在CRT上产生L-视锥和M-视锥隔离视网膜电图（ERG）。该技术的一个主要限制是视锥类的调制深度受到磷光体的受限亮度及其光谱重叠的限制。为了解决这个问题，我们已经将该技术移植到四色LED Ganzfeld刺激（诊断ColorDome）。这允许更高的视网膜照度、更高的对比度和三重无声替换。通过仔细控制视网膜区域的刺激，我们表明，当亮度，大小和锥对比度保持恒定时，可以从CRT和LED刺激记录相同的数据。重要的是，两种器械的不同时间曲线不会影响ERG振幅和相位图。我们目前的数据在一个更广泛的范围内的亮度（高达约10000 troland）和对比与LED刺激器比以前报道的CRT屏幕。我们得出结论，与LED刺激器和CRT屏幕获得的数据之间的密切相似性表明，差异有一个纯粹的生理起源。
Using double silent substitution, it is possible to generate L-cone and M-cone isolating electroretinograms (ERGs) on a CRT. A major limitation of the technique is that the depth of modulation of cone classes is limited by the restricted luminance of the phosphors and their spectral overlap. To address this problem we have ported the technique to a four-color LED Ganzfeld stimulus (Diagnosis ColorDome). This allows higher retinal illuminances, higher contrasts, and triple silent substitution. With careful control over the retinal area stimulated, we show that the same data can be recorded from both CRT and LED stimuli when luminance, size and cone contrast are kept constant. Importantly, the different temporal profiles of the two devices do not influence the ERG amplitude and phase plots. We present data over a much wider range of luminances (up to about 10000 trolands) and contrasts with the LED stimulator than previously reported with CRT screens. We conclude that the close resemblance between data obtained with an LED stimulator and with a CRT screen indicate that the differences have a purely physiological origin.