Comparison of biochemical and questionnaire estimates of tobacco exposure.
Comparison of biochemical and questionnaire estimates of tobacco exposure.
复制标题
烟草暴露的生化和问卷估计的比较。
DOI：
10.1016/0091-7435(79)90026-4
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发表时间：
1979
影响因子：
5.1
通讯作者：
S. Hulley
中科院分区：
文献类型：
--
作者：
T. Vogt;S. Selvin;S. Hulley
在142名男性中检查了习惯性烟草暴露的措施。从吸烟问卷的17个变量进行了测试，其关联的程度和独立性与两个客观的测试，呼气一氧化碳（CO）和血清硫氰酸盐（SCN）的水平。17，吸烟频率是最强的预测生化结果，它占24%的变异指数，结合SCN和CO值。在逐步多元回归分析中，只有另外两个问卷变量提供了额外的信息：自上次吸烟以来的时间（6%）和吸烟者过去戒烟的最长时间（6%）。传统的问卷估计的剂量，如吸入深度，每支香烟的吸烟量，并使用过滤嘴没有贡献显着的信息SCN和CO的多元回归，这一发现证实了协方差分析。CO和SCN分析为调查问卷答复中的烟草暴露估计提供了客观和实用的补充。
Measures of habitual tobacco exposure were examined in 142 men. Seventeen variables from a smoking questionnaire were tested for the magnitude and independence of their associations with two objective tests, the levels of expired air carbon monoxide (CO) and of serum thiocyanate (SCN). Of the 17, cigarette smoking frequency was the strongest predictor of the biochemical results; it accounted for 24% of the variance in an index that combined the SCN and CO values. Only two other questionnaire variables contributed additional information in a stepwise multiple regression analysis: the time elapsed since last smoking (6%) and the longest period the smoker had been off cigarettes in the past (6%). Conventional questionnaire estimates of dosage such as depth of inhalation, the amount of each cigarette smoked, and the use of filters did not contribute significant information to the multiple regression of SCN and CO, and this finding was confirmed by an analysis of covariance. The CO and SCN analyses provide an objective and practical addition to estimates of tobacco exposure from questionnaire responses.