Influence of congenital heart disease on survival in children with congenital diaphragmatic hernia

Influence of congenital heart disease on survival in children with congenital diaphragmatic hernia
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DOI:
10.1067/mpd.2002.125004
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发表时间:
2002-07-01
影响因子:
5.1
通讯作者:
Crombleholme, TM
Crombleholme, TM
中科院分区:
医学2区
文献类型:
--
作者:
Cohen, MS;Rychik, J;Crombleholme, TM

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目的:我们试图评估CDH和HD患者的结局,以确定LHR是否也能预测这一亚组患者的结局。研究设计:我们进行了回顾性研究(1996年4月至2000年10月)(n = 143,82.2%)和HD患者(n = 31,17.8%),以确定其他异常的发生率、至足月生存率、CDH修复率、心脏修复率和至出院生存率。结果:CDH合并HD患者从出生到末次随访的死亡风险是单纯CDH患者的2.9倍(P
Objective: We sought to assess outcome in patients with CDH and HD to determine if LHR is also predictive of outcome in this subset of patients.Study design: We carried out a retrospective review (April 1996-October 2000) of patients with isolated CDH (n = 143, 82.2%) and patients with HD (n = 31, 17.8%) to determine the incidence of additional anomalies, survival to term, CDH repair, cardiac repair, and survival to discharge. Survival based on LHR was analyzed in a subset of fetuses.Results: The risk of death from birth to last follow-up was 2.9 times higher for patients with CDH plus HD than for patients with CDH alone (P