Zinc and selenium levels in women with gestational diabetes mellitus at Medani Hospital, Sudan
Zinc and selenium levels in women with gestational diabetes mellitus at Medani Hospital, Sudan
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DOI：
10.3109/01443615.2014.919576
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发表时间：
2014-10-01
影响因子：
1.3
通讯作者：
Adam, I.
中科院分区：
文献类型：
--
作者：
Hamdan, H. Z.;Elbashir, L. M.;Adam, I.
妊娠糖尿病是妊娠期常见的医学疾病。越来越多的证据表明，锌、硒状况与妊娠期糖尿病之间存在关联。在苏丹Medani医院进行了一项病例对照研究，比较妊娠期糖尿病孕妇和正常孕妇（对照组）的锌和硒水平。两组（每组31例）在年龄、产次、胎龄、血红蛋白和体重指数方面匹配良好。采用原子吸收分光光度法测定锌和硒水平。两组之间的中位（四分位数）锌（498.9 [395-703] vs 486.4 [404-667] m μ g/l，p = 0.905）和硒（164.4 [61-415] vs 204 [68-541] m μ g/l，p = 0.838）值无显著差异。锌和硒之间以及这些微量元素与体重指数、胎龄和血糖水平之间均无显著相关性。
Gestational diabetes is a common medical disorder in pregnancy. There is a growing body of evidence of the association between zinc, selenium status and diabetes mellitus during pregnancy. A case-control study was conducted at Medani Hospital, Sudan, to compare zinc and selenium levels in pregnant women with gestational diabetes and normal pregnant women (controls). The two groups (31 in each arm) were well-matched in age, parity, gestational age, haemoglobin and body mass index. Zinc and selenium levels were measured using atomic absorption spectrophotometry. There were no significant differences in the median (interquartile) zinc (498.9 [395-703] vs 486.4 [404-667] m mu g/l, p = 0.905) and selenium (164.4 [61-415] vs 204 [68-541] m mu g/l, p = 0.838) values between the two groups. There were no significant correlations between zinc and selenium, or between these trace elements and body mass index, gestational age and blood glucose levels.