Electroencephalography of encephalopathy in patients with endocrine and metabolic disorders.
Electroencephalography of encephalopathy in patients with endocrine and metabolic disorders.
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DOI：
10.1097/wnp.0b013e3182a73db9
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发表时间：
2013-10
期刊：
影响因子：
--
通讯作者：
Kaplan PW
中科院分区：
文献类型：
--
作者：
Faigle R;Sutter R;Kaplan PW
由于潜在的代谢毒性或内分泌异常而导致脑病而导致精神状态急性改变的患者经常出现在急症医院中。快速诊断和纠正根本原因至关重要，因为长期的脑病状态预示着不良的结果。正确的诊断和治疗仍然具有挑战性，因为几种脑病可能表现相似，并且进一步的实验室、影像或其他测试可能并不总能揭示根本原因。脑电图 (EEG) 可快速提供有关脑病患者的附加信息。它可能有助于确定诊断，并且对于识别非惊厥性癫痫持续状态是必不可少的——在这种情况下，非惊厥性癫痫持续状态是一种重要的可能并发症。脑电图可以帮助临床医生衡量脑功能障碍的严重程度，并可以帮助预测结果。本综述总结了脑病选定代谢和内分泌原因的脑电图发现的最新知识，并强调了与特定病因相关的独特脑电图特征。
Patients with acute alteration in mental status from encephalopathy due to underlying metabolic-toxic or endocrine abnormalities are frequently seen in the acute hospital setting. A rapid diagnosis and correction of the underlying cause is essential as a prolonged state of encephalopathy portends a poor outcome. Correct diagnosis and management remain challenging because several encephalopathies may present similarly, and further laboratory, imaging or other testing may not always reveal the underlying cause. Electroencephalography (EEG) provides rapid additional information on the encephalopathic patient. It may help establish the diagnosis, and is indispensable for identifying non-convulsive status epilepticus – an important possible complication in this context. The EEG may assist the clinician in gauging the severity of brain dysfunction, and may aid in predicting outcome. This review summarizes the current knowledge on EEG findings in selected metabolic and endocrine causes of encephalopathy, and highlights distinct EEG features associated with particular etiologies.