Aquaporins are observed in the duct epithelia of the epididymal region of the large white turkey.
Aquaporins are observed in the duct epithelia of the epididymal region of the large white turkey.
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在大白火鸡附睾区域的导管上皮中观察到水通道蛋白。
作者：
L. Zaniboni;V. Akuffo;M. Bakst
在鸟类体内，调节支持精子离开睾丸的睾丸液重新摄取的细胞和分子机制尚不清楚。水通道蛋白的存在，参与跨膜水运输的蛋白质，被调查。观察仅限于输出管、集合管和附睾管。有趣的是，所有这些导管都呈水通道蛋白-2、-3和-9阳性，而不是水通道蛋白-7。阳性时，水通道蛋白定位于整个细胞或非纤毛细胞的顶端质膜以及纤毛细胞的顶端质膜和纤毛。这项研究首次清楚地证明了水通道蛋白-2、-3和-9存在于任何鸟类的附睾区。我们推测水通道蛋白在浓缩精子和促进附睾区精子成熟方面起作用。
The cellular and molecular mechanisms regulating the reuptake of the testicular fluid supporting sperm exiting the testes in the bird are not known. The presence of aquaporins, proteins involved in transmembrane water transport, was investigated. Observations were limited to the ductuli efferentes, collecting ducts, and ductus epididymis. Interestingly all of these ducts were positive for aquaporins-2, -3, and -9 but not aquaporin-7. When positive, aquaporin was observed localized over the whole cell or the apical plasma membrane of the nonciliated cells and the apical plasma membrane and cilia of the ciliated cells. This study is the first to clearly demonstrate the presence of aquaporins-2, -3, and -9 in the epididymal region of any bird. We assume the aquaporins play a role in concentrating the sperm and in the promotion of sperm maturation in the epididymal region.
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DOI：
10.1006/bbrc.1997.7664
发表时间：
1997-11-17
影响因子：
3.1
作者：
Ma, TH;Yang, BX;Verkman, AS
通讯作者：
Verkman, AS
DOI：
10.1152/ajpcell.1998.275.1.c216
发表时间：
1998-07-01
影响因子：
5.5
作者：
Nelson, RD;Stricklett, P;Kohan, DE
通讯作者：
Kohan, DE
DOI：
10.1073/pnas.91.23.10997
发表时间：
1994-11-08
影响因子：
11.1
作者：
ECHEVARRIA, M;WINDHAGER, EE;FRINDT, G
通讯作者：
FRINDT, G
DOI：
10.1152/ajprenal.1999.277.5.f685
发表时间：
1999-11-01
影响因子：
4.2
作者：
Tsukaguchi, H;Weremowicz, S;Hediger, MA
通讯作者：
Hediger, MA