Optical-transparent and flexible glucose sensor with ITO electrode
Optical-transparent and flexible glucose sensor with ITO electrode
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DOI：
10.1016/s0956-5663(03)00130-1
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发表时间：
2003-10-30
影响因子：
12.6
通讯作者：
Endo, T
中科院分区：
文献类型：
--
作者：
Mitsubayashi, K;Wakabayashi, Y;Endo, T
将葡萄糖氧化酶(GOD)与戊二醛溶液固定在透明氧电极的敏感区，构建了葡萄糖传感器。用金属可焊膜和涂有Ag/AgCl电极的透气膜封接了含铟锡氧化物(ITO)电极的KCI电解液，制成了氧电极。在计算机控制的恒电位仪的批量测量系统中，使用标准葡萄糖溶液对传感器的性能进行了评估，还原电位为-900 mV。该传感器结构灵活，在400~700 nm的可见光范围内具有良好的光学透明性(小于0.6abs)。该传感器可用于测量0.06~1.24mmol.L范围内的血糖(相关系数：0.999)，包括报道的正常人泪液葡萄糖浓度(0.14mmol.L)，具有良好的重复性。(C)2003 Elsevier Science B.V.保留所有权利。
The glucose sensor was constructed by immobilizing glucose oxidase (GOD) with glutaraldehyde solution onto the sensitive area of the transparent oxygen electrode. The oxygen electrode was fabricated by sealing KCI electrolyte solution including the Indium-Tin Oxide (ITO)-electrode with both metal-weldable film and gas-permeable membrane coated with Ag/AgCl electrode. The sensor behavior was evaluated using standard glucose solutions in a batch measurement system with a computer-con trolled potentiostat at a reduction potential of -900 mV. The sensor device has flexible structure and good optical transparency (less than 0.6 abs) at the visible waveleneth from 400 to 700 nm. The sensor was possible to be used for measuring glucose from 0.06 to 1.24 mmol/l (correlation coefficient: 0.999), including the reported concentration of tear glucose in normal (0.14 mmol/l), with good reproducibility. (C) 2003 Elsevier Science B.V. All rights reserved.