Parenchymal stability.
Parenchymal stability.
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实质稳定性。
DOI：
10.1152/jappl.1992.73.2.596
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Wilson,TA
中科院分区：
文献类型：
--
作者：
Stamenovic,D;Wilson,TA
连续介质模型和细观力学模型已被用来描述肺实质的力学。不同的作者，使用不同的模型，得出了不同的结论，实质的稳定性。我们表明，连续介质模型，增加了从最近的微观力学建模获得的弹性模量的界限，产生相同的结论已经从纯粹的微观力学建模获得的稳定性：如果肺是均匀的，它将是稳定的;局部肺不张不会发生在积极的经肺压力。然而，相同的分析产生的预测，如果整个肺的表面积与体积的比例是不均匀的，如果表面张力是大的，表面密度较高的区域塌陷，表面积不敏感。一个微观力学模型，说明区域崩溃。
Both continuum and micromechanical models have been used to describe the mechanics of lung parenchyma. Different authors, using different models, have come to different conclusions about parenchymal stability. We show that the continuum model, augmented by bounds on the elastic moduli obtained from recent micromechanical modeling, yields the same conclusions about stability that have been obtained from purely micromechanical modeling: if the lung were homogeneous, it would be stable; local atelectasis would not occur at positive transpulmonary pressure. However, the same analysis yields the prediction that if the surface-to-volume ratio is not uniform throughout the lung, regions of higher surface density collapse if surface tension is large and insensitive to surface area. A micromechanical model that illustrates regional collapse is described.