Glucose Metabolism in Outpatients with New-Onset Hypertension in Chinese Han Population

Glucose Metabolism in Outpatients with New-Onset Hypertension in Chinese Han Population
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中国汉族人群门诊新发高血压患者的糖代谢

DOI:
10.3109/10641963.2012.666601
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发表时间:
2012-01-01
影响因子:
12.3
通讯作者:
Jiang, Shisen
Jiang, Shisen
中科院分区:
医学4区
文献类型:
--
作者:
Gu, Ping;Jiang, Weimin;Jiang, Shisen

文献摘要

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本研究的目的是评估中国汉族人群中未经治疗的新发高血压患者血糖异常的患病率。499例新发高血压患者(无糖尿病)入组本研究。在既往无糖尿病史的新发高血压患者中,57.1%的患者被诊断为糖代谢异常。按年龄分层,糖尿病和糖尿病前期患病率随年龄增长而增加。Logistic回归分析显示,男性、高龄、高甘油三酯、胰岛素抵抗水平稳态模型评估均与新发高血压患者糖尿病前期或糖尿病风险增加显著相关。
The aim of this study was to assess the prevalence of glucose abnormalities in a Chinese Han population with untreated new-onset hypertension. Four hundred and ninety-nine new-onset hypertensive patients without diabetes were enrolled in this study. An abnormal glucose metabolism was diagnosed in 57.1% of the new-onset hypertensive patients without previously diagnosed diabetes. Stratified by age, the prevalence of diabetes and prediabetes were increased with aging. Male sex, advanced age, higher serum triglycerides, and homeostasis model assessment of insulin resistance levels were all significantly associated with the increased risks of pre-diabetes or diabetes in new-onset hypertensive patients when analyzed by the logistic regression analysis.