The effect of protein adsorption on the friction behavior of ultra-high molecular weight polyethylene
The effect of protein adsorption on the friction behavior of ultra-high molecular weight polyethylene
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DOI：
10.1115/ijtc2006-12164
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发表时间：
2006-06
影响因子：
3.2
通讯作者：
K. Karuppiah;S. Sundararajan;Zhihui Xu;Xiaodong Li
中科院分区：
文献类型：
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作者：
K. Karuppiah;S. Sundararajan;Zhihui Xu;Xiaodong Li
将经过两种不同表面处理（研磨和熔化/重整）的医用级 UHMWPE 样品暴露于 10% 牛血清白蛋白溶液中，并使用原子力显微镜量化它们的摩擦响应。暴露于蛋白质时观察到的摩擦力增加归因于表面上变性蛋白质层的形成。改变 UHMWPE 的结晶度和表面能会影响蛋白质吸附机制以及由此导致的摩擦行为的增加。
Medical-grade UHMWPE samples with two different surface finishing treatments, milling and melting/reforming were exposed to 10% bovine serum albumin solution and their friction responses were quantified using atomic force microscopy. The observed friction increase upon exposure to proteins was attributed to the formation of a layer of denatured proteins on the surface. Changing the crystallinity and surface energy of UHMWPE affected the protein adsorption mechanism and the resulting increase in friction behavior.