Copper-catalyzed enantioselective C-H functionalization of indoles with an axially chiral bipyridine ligand
Copper-catalyzed enantioselective C-H functionalization of indoles with an axially chiral bipyridine ligand
复制标题
铜催化轴向手性联吡啶配体对吲哚进行对映选择性 C-H 官能化
DOI：
10.1039/c6ob01516f
复制
发表时间：
2016-09-21
影响因子：
3.2
通讯作者：
Zhou, Yong-Gui
中科院分区：
文献类型：
--
作者：
Gao, Xiang;Wu, Bo;Zhou, Yong-Gui
以铜与轴向手性联吡啶配体C4-ACBP的配合物为催化剂，发展了吲哚与重氮化合物的不对称功能化反应，ee值高达95%，为该类配体的进一步应用奠定了基础。
Using copper complexes with an axially chiral bipyridine ligand C4-ACBP as the catalyst, an enantioselective functionalization of indoles with diazo compounds was developed with up to 95% ee. This protocol paves the way for further applications of these ligands.