Focal liver lesions: Pattern-based classification scheme for enhancement at arterial phase CT

Focal liver lesions: Pattern-based classification scheme for enhancement at arterial phase CT
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DOI:
10.1148/radiology.215.3.r00jn03746
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发表时间:
2000-06-01
期刊:
影响因子:
19.7
通讯作者:
Jain, KA
Jain, KA
中科院分区:
医学1区
文献类型:
--
作者:
Nino-Murcia, M;Olcott, EW;Jain, KA

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目的:介绍我们根据计算机断层扫描 (CT) 动脉期表现的增强模式对局灶性肝脏病变进行分类的早期经验,并确定特定的增强模式是否提示特定的诊断。 材料和方法:作者回顾了 100 名连续患有局灶性肝脏病变的患者的动脉期 CT 图像,不包括单纯性囊肿。每个患者的主要或代表性病变的增强模式被三名对确诊结果不知情的放射科医生分为五类之一:均匀、异常内血管或杂色、周围水坑、完整环或不完整环。单独记录未增强的病灶。所有情况均以协商一致方式达成。参考标准包括组织学检查、相关影像学或临床和影像学随访的结果。结果:100 个病变中有 92% 表现出动脉期强化。与 82% 或更高的阳性预测值和 80% 或更高的特异性相关的模式包括异常内血管或杂色(肝细胞癌)、外周水坑(血管瘤)和完整环(转移)。 结论:增强动脉期肝脏病变的出现对于确定具体诊断具有潜在用途。本研究中使用的分类方案可能是解释动脉期 CT 研究的有用工具。
PURPOSE: To present our early experience with a classification scheme for categorizing focal liver lesions on the basis of the enhancement patterns that they exhibit in the arterial phase of computed tomography (CT) and to determine whether particular enhancement patterns suggest particular diagnoses.MATERIALS AND METHODS: The authors reviewed arterial phase CT images in 100 consecutive patients with focal liver lesions, excluding simple cysts. The enhancement pattern of the dominant or representative lesion in each patient was classified into one of five categories-homogeneous, abnormal internal vessels or variegated, peripheral puddles, complete ring, or incomplete ring-by three radiologists blinded to the proved diagnosis. Lesions without enhancement were recorded separately. Agreement was reached by consensus in all cases. Standards of reference included findings at histologic examination, correlative imaging, or clinical and imaging follow-up.RESULTS: Ninety-two percent of the 100 lesions demonstrated arterial phase enhancement. Patterns associated with positive predictive values of 82% or greater and specificity of 80% or greater included abnormal internal vessels or variegated (hepatocellular carcinoma), peripheral puddles (hemangioma), and complete ring (metastasis).CONCLUSION: The appearance of hepatic lesions in the arterial phase of enhancement has potential use in the determination of specific diagnoses. The classification scheme used in this study may be a useful tool for the interpretation of arterial phase CT studies.