Chinese women's preferences for prenatal diagnostic procedure and their willingness to trade between procedures
Chinese women's preferences for prenatal diagnostic procedure and their willingness to trade between procedures
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DOI：
10.1002/pd.2394
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发表时间：
2009-12-01
影响因子：
3
通讯作者：
Lau, Tze Kin
中科院分区：
文献类型：
--
作者：
Chan, Yiu Man;Sahota, Daljit Singh;Lau, Tze Kin
目的评估中国妇女的偏好选择产前诊断测试，核型分析或快速非整倍体，其与产妇的心理state.Study设计300同意妇女完成了自填式结构问卷，记录他们的心理状态和他们的首选选择的诊断测试染色体异常的离散选择实验设计。诊断测试进行了分类，根据三个属性：染色体信息的完整性，程序到结果的时间间隔和cost.Results参与者表示对核型测试的偏好，无论成本和程序到结果的时间间隔。染色体核型分析提供的额外信息比快速非整倍体分析提供的额外信息的价值为267.82磅（95% CI 226.71-323.31）。只有在结果比核型分析早18天的情况下，女性才会接受快速非整倍体检测。在诊断测试之间进行交易的妇女中，染色体外信息的价值降低到153.83磅（95%CI 125.81-192.19）。高特质焦虑分数（>40）的妇女没有优先选择一个tests.Conclusion中国妇女表现出强烈的偏好，对执行一个完整的染色体核型测试，并有完整的染色体评估进行妊娠。版权所有（C）2009约翰威利父子有限公司
Objective To assess Chinese women's preference for the choice of a prenatal diagnosis test, karyotyping or rapid aneuploidy, and its relationship to maternal psychological state.Study design Three hundred consenting women completed a self administered structured questionnaire which documented their psychological state and their preferred choice of diagnostic test for chromosomal abnormality using a discrete choice experiment design. Diagnostic tests were categorised according to three attributes: completeness of chromosomal information, procedure-to-result time interval and cost.Results Participants indicated a preference towards the karyotype test irrespective of cost and procedure-to-result time interval. The value of obtaining the extra information provided by karyotyping above that of rapid aneuploidy was 267.82 pound (95% CI 226.71-323.31). Women would only accept the rapid aneuploidy test if results where available 18 days sooner than if they were undergoing a karyotyping test. Among women who traded between diagnostic tests, the value of extra chromosomal information was reduced to 153.83 pound (95% CI 125.81-192.19). Women with high trait anxiety scores (>40) did not preferentially select one test.Conclusion Chinese women showed a strong preference towards performing a full karyotype test and having a full chromosomal assessment performed for their pregnancy. Copyright (C) 2009 John Wiley & Sons, Ltd.