A knowledge synthesis of patient and public involvement in clinical practice guidelines: study protocol
A knowledge synthesis of patient and public involvement in clinical practice guidelines: study protocol
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DOI：
10.1186/1748-5908-4-30
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发表时间：
2009-06-04
影响因子：
7.2
通讯作者：
Burgers, Jako
中科院分区：
文献类型：
--
作者：
Legare, France;Boivin, Antoine;Burgers, Jako
背景：未能使患者的偏好和价值观以及社会规范与临床实践指南(CPGs)的建议协调一致，可能会阻碍其在临床实践中的实施。然而，对CPGs制定和实施中的患者和公众参与计划(PPIP)知之甚少。这项研究旨在确定PPIP的作用是什么，在哪些情况下PPIP最有可能有效，以及PPIP如何被认为能够更好地开发和实施CPG。方法和设计：知识合成将分四个阶段进行。在第一阶段，将通过书目数据库搜索关于CPGs发展中的PPIP的文献。还将通过相关组织的邮寄名单发出参考书目和未出版报告的征集。符合条件的出版物将包括原始的定性、定量或混合方法研究设计，报告与CPGs开发或实施有关的PPIP。它们还将包括由CPGs组织制作的描述其PPIP的文件。在第二阶段，根据方案的逻辑模型，两名独立的审查员将提取数据，以收集关于PPIP的主要组成部分和活动、所需资源、PPIP开发和测试的背景以及PPIP基础假设的信息。将对所有保留的出版物进行质量评估。我们的文献检索将辅之以对关键告密者的采访，这些信息来自有目的的CPGs开发人员和患者/公众代表的样本。在第三阶段，我们将使用模板内容分析从出版物和访谈数据中综合证据，将确定的组成部分组织在PPIP理论的有意义的框架中。在面对面的研讨会期间，将与不同的利益相关者验证调查结果，并将完善面向CPGs开发人员的最终工具包。讨论：拟议的研究项目将是基于广泛的出版物和关键线人访谈，在CPGs的开发和实施中探索PPIP的首批项目之一。预计拟议研究产生的结果将大大有助于改进CPGs与患者偏好和价值观以及社会规范之间的协调。
Background: Failure to reconcile patient preferences and values as well as social norms with clinical practice guidelines (CPGs) recommendations may hamper their implementation in clinical practice. However, little is known about patients and public involvement programs (PPIP) in CPGs development and implementation. This study aims at identifying what it is about PPIP that works, in which contexts are PPIP most likely to be effective, and how are PPIP assumed to lead to better CPGs development and implementation.Methods and design: A knowledge synthesis will be conducted in four phases. In phase one, literature on PPIP in CPGs development will be searched through bibliographic databases. A call for bibliographic references and unpublished reports will also be sent via the mailing lists of relevant organizations. Eligible publications will include original qualitative, quantitative, or mixed methods study designs reporting on a PPIP pertaining to CPGs development or implementation. They will also include documents produced by CPGs organizations to describe their PPIP. In phase two, grounded in the program's logic model, two independent reviewers will extract data to collect information on the principal components and activities of PPIP, the resources needed, the contexts in which PPIP were developed and tested, and the assumptions underlying PPIP. Quality assessment will be made for all retained publications. Our literature search will be complemented with interviews of key informants drawn from of a purposive sample of CPGs developers and patient/public representatives. In phase three, we will synthesize evidence from both the publications and interviews data using template content analysis to organize the identified components in a meaningful framework of PPIP theories. During a face-to-face workshop, findings will be validated with different stakeholder and a final toolkit for CPGs developers will be refined.Discussion: The proposed research project will be among the first to explore the PPIP in CPGs development and implementation based on a wide range of publications and key informants interviews. It is anticipated that the results generated by the proposed study will significantly contribute to the improvement of the reconciliation of CPGs with patient preferences and values as well as with social norms.