Determination of triazine herbicides and their metabolites in multiple medicinal parts of traditional Chinese medicines using streamlined pretreatment and UFLC-ESI-MS/MS
Determination of triazine herbicides and their metabolites in multiple medicinal parts of traditional Chinese medicines using streamlined pretreatment and UFLC-ESI-MS/MS
复制标题
简化预处理和UFLC-ESI-MS/MS测定中药多个药用部位中的三嗪类除草剂及其代谢物
DOI：
10.1016/j.chemosphere.2017.09.085
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发表时间：
2018-01-01
期刊：
影响因子：
8.8
通讯作者：
Yang, Meihua
中科院分区：
文献类型：
--
作者：
Liu, Congmin;Dou, Xiaowen;Yang, Meihua
A rapid, sensitive, and reliable ultra-fast liquid chromatography combined with electrospray ionization tandem mass spectrometry (UFLC-ESI-MS/MS) method was established and applied to simultaneous determination of 31 triazine herbicides and their metabolites in multiple medicinal parts of traditional Chinese medicines (TCMs). A streamlined pretreatment approach using one-step extraction and dilution was proposed, which provided high-throughput processing, excellent recovery, and negligible interference. Afterwards, multiple-reaction monitoring (MRM) and information-dependent acquisition (IDA) triggered enhanced product ion spectra (EPI) was adopted to identify and quantify the targets in a single analysis. The optimized method was then validated according to the guidelines of the European Commission for the following parameters: Matrix effects, specificity, accuracy, precision, linearity, range, and stability. The LOD and LOQ for the 31 triazine herbicides were 0.1-10 mu g kg(-1) and 0.5-25 mu g kg(-1), respectively. Recoveries at three concentration levels were within 67.9-120.3% with an associated precision RSD
