Ambient wood smoke, traffic pollution and adult asthma prevalence and severity
Ambient wood smoke, traffic pollution and adult asthma prevalence and severity
复制标题
DOI：
10.1111/resp.12108
复制
发表时间：
2013-10-01
期刊：
影响因子：
6.9
通讯作者：
Dharmage, Shyamali C.
中科院分区：
文献类型：
--
作者：
Bui, D. Son;Burgess, John A.;Dharmage, Shyamali C.
背景与目的环境木材烟雾和交通相关空气污染对成人哮喘的影响尚未得到很好的研究。本文旨在调查暴露于周围的木材烟雾，交通相关的空气污染和当前哮喘/哮喘严重程度之间的关联，以及是否有任何关联被特应性状态所改变。周围木材烟雾与两种交通相关空气污染指数之间的关系（重型车辆在家附近的频率和强烈的交通噪声的频率）和当前哮喘/哮喘严重程度进行了调查。无条件Logistic回归，以检查当前的哮喘和有序Logistic回归，以检查哮喘severitywasused.Resultsfor哮喘患者，暴露于环境木材烟雾（比值比1.11; 95%置信区间1.02-1.20）和经常暴露于重型车辆（比值比1.80; 95%置信区间1.09-2.96）与哮喘严重程度增加。两种关联均不随特应性状态而变化。结论：在中年人中，周围的木材烟雾和交通污染与哮喘严重程度增加有关。这些发现表明，避免或限制暴露于交通污染和木材烟雾可能有助于减少哮喘。未来的研究重复这一发现的建议，并应检查这种影响的具体生物学机制。
Background and objectiveThe impact of ambient wood smoke and traffic-related air pollution on adult asthma has not been well studied. This paper aims to investigate associations between exposure to ambient wood smoke, traffic-related air pollution and current asthma/asthma severity in middle age, and whether any associations are modified by atopic status.MethodsUsing data from the Tasmanian Longitudinal Health Study, associations between ambient wood smoke and two indices of traffic-related air pollution (frequency of heavy vehicles near the home and frequency of intense traffic noise) and current asthma/asthma severity were investigated. Unconditional logistic regression to examine current asthma and ordinal logistic regression to examine asthma severity was used.ResultsFor asthmatics, both exposure to ambient wood smoke (odds ratio 1.11; 95% confidence interval 1.02-1.20) and being frequently exposed to heavy vehicles (odds ratio 1.80; 95% confidence interval 1.09-2.96) were associated with increased asthma severity. Neither association varied by atopic status.ConclusionsIn middle-aged adults, ambient wood smoke and traffic pollution were associated with increased asthma severity. These findings suggest that avoiding or limiting exposure to traffic pollution and wood smoke may help to reduce asthma. Future studies to replicate this finding are recommended and should examine specific biological mechanisms for this effect.