Polycyclic aromatic hydrocarbons in foods:: Human exposure through the diet in Catalonia, Spain
Polycyclic aromatic hydrocarbons in foods:: Human exposure through the diet in Catalonia, Spain
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DOI：
10.4315/0362-028x-66.12.2325
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发表时间：
2003-12-01
影响因子：
2
通讯作者：
Müller, L
中科院分区：
文献类型：
--
作者：
Falcó, G;Domingo, JL;Müller, L
计算了西班牙加泰罗尼亚地区普通人群膳食中16种多环芳烃(PAHs)的摄入量，这些多环芳烃(PAHs)包括：萘、萘、蒽、荧烯、菲、菲、荧蒽、苯并[b]荧菲、苯并[k]荧菲、苯并[a]芘、二苯并[a，h]菲、苯并[g，h，i]茂和铟并[1，2，3-c，d]芘。对2000年6-8月在加泰罗尼亚7个城市随机采集的食品样品中多环芳烃的浓度进行了测定。这项研究包括了11个食物组。采用高效液相色谱法对多环芳烃进行了分析。计算了儿童、青少年、成年男性、成年女性和老年人这五个人群的总多环芳烃和致癌多环芳烃的膳食摄入量。在所分析的多环芳烃中，以菲(16.7µg/kg)和芘(10.7µg/kg)为主。按食物类别划分，谷物(14.5杯/公斤)和肉及肉制品(13.4杯/公斤)的多环芳烃总量最高。这16种多环芳烃的平均估计膳食摄入量如下：男性成人8.4杯/天；青少年8.2杯/天；儿童7.4杯/天；老年人6.3杯/天；女性成年人6.3杯/天。计算出的多环芳烃每日摄入量与体重为70公斤的成年男性患癌症的风险增加5/10(6)有关。
The dietary intake of 16 polycyclic aromatic hydrocarbons (PAHs) (naphthalene, acenaphthylene, acenaphthene, fluorene, phenanthrene, anthracene, fluoranthene, pyrene, benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]anthracene, benzo[g,h,i]perylene, and indeno[1,2,3-c,d]pyrene) by the general population of Catalonia, Spain, was calculated. Concentrations of PAHs in food samples randomly acquired in seven cities of Catalonia from June to August 2000 were measured. Eleven food groups were included in the study. High-performance liquid chromatography was used to analyze PAHs. The dietary intakes of total and carcinogenic PAHs was calculated for five population groups: children, adolescents, male adults, female adults, and seniors. Among the analyzed PAHs, there was a predominance of phenanthrene (16.7 mug/kg) and pyrene (10.7 mug/kg). By food group, the highest levels of total PAHs were detected in cereals (14.5 mug/kg) and in meat and meat products (13.4 mug/kg). The mean estimated dietary intake of the sum of the 16 PAHs was as follows: male adults, 8.4 mug/day; adolescents, 8.2 mug/day; children, 7.4 mug/day; seniors, 6.3 mug/day; female adults, 6.3 mug/day. The calculated daily intake of PAHs would be associated with a 5/10(6) increase in the risk for the development of cancer in a male adult with a body weight of 70 kg.