Cardiovascular risk factors and excess adiposity among overweight children and adolescents: The Bogalusa Heart Study
Cardiovascular risk factors and excess adiposity among overweight children and adolescents: The Bogalusa Heart Study
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DOI：
10.1016/j.jpeds.2006.08.042
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发表时间：
2007-01-01
影响因子：
5.1
通讯作者：
Dietz, William H.
中科院分区：
文献类型：
--
作者：
Freedman, David S.;Mei, Zuguo;Dietz, William H.
目的探讨不同体质指数（BMI）临界值对儿童肥胖的诊断价值（基于皮褶厚度），血脂、胰岛素和血压的不良水平，以及严重成人肥胖的高风险。（n = 10，099）和纵向在参与博加卢萨心脏研究的受试者中进行了（n = 2392）分析。在疾病控制中心（CDC）的生长图表中，39%的人至少有两个危险因素，65%的人过度肥胖，65%的人成年BMI为2：35 kg/m2。在BMI >= 99（th）P的人群中，59%的人至少有两个危险因素，94%的人过度肥胖，88%的人成年BMI为35 kg/m2。在美国，大约4%的儿童现在有BMI >= 99（th）P。结论年龄BMI的99（th）P可能适合于识别生化异常和严重成人肥胖的高风险儿童。更积极的体重控制策略可能是必要的，这一亚组。
Objective To explore the accuracy of various body mass index (BMI) cutpoints in identifying children who have excess adiposity (based on skinfold thicknesses), adverse levels of lipids, insulin, and blood pressures, and a high risk for severe adult obesity.Study design Cross-sectional (n = 10,099) and longitudinal (n = 2392) analyses were performed among subjects who participated in the Bogalusa Heart Study.Results Of children with a BMI >= 95(th) percentile (P) of the Centers for Disease Control (CDC) growth charts, 39% had at least two risk factors, 65% had excess adiposity, and 65% had an adult BMI of 2:35 kg/m(2). Of those with a BMI >= 99(th) P, 59% had at least two risk factors, 94% had excess adiposity, and 88% had an adult BMI of 35 kg/m(2). About 4% of children in the US now have a BMI >= 99(th) P.Conclusions The 99(th) P of BMI-for-age may be appropriate for identifying children who are at very high risk for biochemical abnormalities and severe adult obesity. More aggressive weight control strategies may be warranted for this subgroup.