SH3 - AN ABUNDANT PROTEIN DOMAIN IN SEARCH OF A FUNCTION
SH3 - AN ABUNDANT PROTEIN DOMAIN IN SEARCH OF A FUNCTION
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DOI：
10.1016/0014-5793(92)80901-r
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发表时间：
1992-07-27
期刊：
影响因子：
3.5
通讯作者：
SARASTE, M
中科院分区：
文献类型：
--
作者：
MUSACCHIO, A;GIBSON, T;SARASTE, M
Src-同源性3是约60个氨基酸残基的小蛋白质结构域。它可能是由β-片层组成的。SH 3存在于许多真核蛋白中，参与信号转导、细胞极化和膜-细胞骨架相互作用。在这里，我们回顾它的发生，并讨论这个域的可能功能。
Src-homology 3 is a small protein domain of about 60 amino acid residues. It is probably made of beta-sheets. SH3 is present in a large number of eukaryotic proteins which are involved in signal transduction, cell polarization and membrane-cytoskeleton interactions. Here we review its occurrence and discuss possible functions of this domain.