ANTIBIOTIC THERAPY OF BACTERIAL ENDOCARDITIS .6. SUBACUTE ENTEROCOCCAL ENDOCARDITIS - CLINICAL, PATHOLOGIC AND THERAPEUTIC CONSIDERATION OF 33 CASES
ANTIBIOTIC THERAPY OF BACTERIAL ENDOCARDITIS .6. SUBACUTE ENTEROCOCCAL ENDOCARDITIS - CLINICAL, PATHOLOGIC AND THERAPEUTIC CONSIDERATION OF 33 CASES
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DOI：
10.1161/01.cir.10.2.173
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发表时间：
1954-01-01
期刊：
影响因子：
37.8
通讯作者：
MARTIN, WJ
中科院分区：
文献类型：
--
作者：
GERACI, JE;MARTIN, WJ
本文回顾了从1944年1月到1953年12月这十年间所遇到的33例肠球菌性心内膜炎病例。体外研究表明，青霉素和链霉素是抗菌效果最好的抗生素对，14例患者中12例（86%）治愈，10例联合治疗。肠球菌性心内膜炎的治愈率现在接近青霉素敏感链球菌引起的心内膜炎的治愈率。马克斯。号码。每一种治疗都是通过个体化治疗来实现的。青霉素的每日剂量和青霉素-链霉素联合治疗的持续时间应以采用患者肠球菌菌株的体外杀菌试验为指导。
Thirty-three cases of enterococcal endocarditis encountered during the decade from January 1944 through December 1953 are reviewed. In vitro studies indicate that penicillin and streptomycin is the best antibiotic pair for bactericidal effect Twelve of the last 14 patients were cured (86%), 10 with combined therapy. The cure rate in enterococcal endocarditis now approximates that of endocarditis caused by penicillin sensitive streptococci. A max. number. of cures is achieved by individualization of therapy. The daily dosage of penicillin and the duration of combined penicillin-streptomycin therapy should be guided by in vitro bactericidal tests employing the patient''s strain of enterococcus.