New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity.
New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity.
复制标题
DOI:
10.1017/s1092852913000801
复制
发表时间:
2014-02
期刊:
影响因子:
3.3
通讯作者:
Potenza, Marc N.
中科院分区:
文献类型:
--
作者:
Fineberg, Naomi A.;Chamberlain, Samuel R.;Goudriaan, Anna E.;Stein, Dan J.;Vanderschuren, Louk J. M. J.;Gillan, Claire M.;Shekar, Sameer;Gorwood, Philip A. P. M.;Voon, Valerie;Morein-Zamir, Sharon;Denys, Damiaan;Sahakian, Barbara J.;Moeller, F. Gerard;Robbins, Trevor W.;Potenza, Marc N.
Impulsivity and compulsivity represent useful conceptualizations that involve dissociable cognitive functions, mediated by neuroanatomically and neurochemically distinct components of cortico-subcortical circuitry. The constructs were historically viewed as diametrically opposed, with impulsivity being associated with risk-seeking and compulsivity with harm-avoidance. However, they are increasingly recognized to be linked by shared neuropsychological mechanisms involving dysfunctional inhibition of thoughts and behaviors. In this paper, we selectively review new developments in the investigation of the neurocognition of impulsivity and compulsivity in humans, in order to advance our understanding of the pathophysiology of impulsive, compulsive and addictive disorders and indicate new directions for research.