The Pfam protein families database
The Pfam protein families database
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DOI：
10.1093/nar/gkm960
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发表时间：
2008-01-01
影响因子：
14.9
通讯作者：
Bateman, Alex
中科院分区：
文献类型：
--
作者：
Finn, Robert D.;Tate, John;Bateman, Alex
Pfam是蛋白质结构域和家族的综合集合，以多序列比对和轮廓隐马尔可夫模型表示。目前发布的Pfam（22.0）包含9318个蛋白质家族。Pfam现在不仅基于UniProtKB序列数据库，还基于NCBI GenPept和来自选定元组学项目的序列。联合会成员在联合王国（http：//pfam.sanger.ac.uk/）、美国（http：//pfam.janelia.org/）和瑞典（http：//pfam.sbc.su.se/）使用新的、一致的和改进的网站设计，以及法国（http：//pfam.jouy.inra.fr/）和韩国（http：//pfam.ccbb.re.kr/）的镜像网站都可以在网上查阅该基金。
Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam ( 22.0) contains 9318 protein families. Pfam is now based not only on the UniProtKB sequence database, but also on NCBI GenPept and on sequences from selected metage-nomics projects. Pfam is available on the web from the consortium members using a new, consistent and improved website design in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/), as well as from mirror sites in France (http://pfam.jouy.inra.fr/) and South Korea (http://pfam.ccbb.re.kr/).