Gene pyramiding as a Bt resistance management strategy : How sustainable is this strategy ?
Gene pyramiding as a Bt resistance management strategy : How sustainable is this strategy ?
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基因金字塔作为 Bt 抗性管理策略：该策略的可持续性如何？
DOI：
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
J. Smith
中科院分区：
文献类型：
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作者：
J. Smith
关于昆虫对苏云金芽孢杆菌δ内毒素产生抗药性的报告对基于Bt毒素的害虫管理技术的可持续性提出了质疑。企业界已经通过包括基因测序在内的创新来应对这一挑战。聚合需要堆叠多个基因，导致在转基因品种中同时表达一种以上的毒素。由于杀虫剂混合物的使用表明，交叉抗性和/或多重抗性可能使这种战略在长期内不那么有效，因此人们对基因杀虫剂的可持续性提出了疑问。目前昆虫种群遗传学的理论和实践证据表明，基因改造本身不能作为一种抗性管理策略。聚合是有用的策略，以扩大在每个转基因品种控制的害虫的范围，它仍然需要部署在与Bt抗性管理策略，如作物避难所，生物害虫控制，时间和空间作物轮作等。
Reports on the emergence of insect resistance to Bacillus thuringiensis delta endotoxins have raised doubts on the sustainability of Bt-toxin based pest management technologies. Corporate industry has responded to this challenge with innovations that include gene pyramiding among others. Pyramiding entails stacking multiple genes leading to the simultaneous expression of more than one toxin in a transgenic variety. Questions have been raised on the sustainability of gene pyramiding since the use of insecticide mixtures has shown that cross resistance and/or multiple resistance can render such strategies to be less effective in the long term. Current theoretical and practical evidence in insect population genetics suggest that gene pyramiding cannot be sustained as a resistance management strategy per se. Pyramiding is useful as a strategy to broaden the range of insect pests controlled in each transgenic variety, and it still has to be deployed in tandem with Bt resistance management strategies such as crop refugia, biological pest control, temporal and spatial crop rotations among others.
过氧化氢光解灭菌法对蜡样芽孢杆菌芽孢的杀芽作用
DOI：
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发表时间：
2022
期刊：
影响因子：
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作者：
宍戸駿一;白土翠;倉内美智子;中村圭祐;菅野太郎;庭野吉己
通讯作者：
庭野吉己