Acne prevalence and beyond: acne disability and its predictive factors among Chinese late adolescents in Hong Kong
Acne prevalence and beyond: acne disability and its predictive factors among Chinese late adolescents in Hong Kong
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DOI：
10.1111/j.1365-2230.2009.03340.x
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发表时间：
2010-01-01
影响因子：
4.1
通讯作者：
Molinari, N.
中科院分区：
文献类型：
--
作者：
Law, M. P. M.;Chuh, A. A. T.;Molinari, N.
背景。中国青春期后期患者痤疮的患病率、其对生活质量（QOL）的影响以及治疗使用情况的数据缺乏。目的。获取有关香港华人晚期青少年痤疮患病率和预测因素、痤疮引起的残疾以及治疗选择的数据。方法。这是一项对香港一所大学的 389 名入学者进行随机抽样的横断面研究，使用全球痤疮分级系统 (GAGS) 来衡量痤疮的临床严重程度，并使用卡迪夫痤疮残疾指数 (CADI) 来衡量生活质量。答复率为99.3%。痤疮患病率为 81.5% (95% CI 77.6-85.4%)，痤疮致残率较高，为 81.8% (95% CI 78.1-85.6%)。痤疮临床严重程度的评估与 QOL 的影响没有很强的相关性（gamma = 0.445，P < 0.001）。过去6个月内，30.3%的受试者使用过局部治疗，3.9%的受试者使用过全身常规西药，3.2%的受试者使用过中药。使用多变量逻辑回归来探索痤疮残疾的预测因素。女性 (P = 0.002)、较高的 GAGS 评分 (P < 0.001)、较高的感知压力 (P = 0.01) 以及愿意为假设的永久治愈支付 15 000 (970) 英镑的意愿 (P = 0.03) 是积极的预测因素。结论。痤疮在香港很普遍，对心理影响相当大。临床严重程度与生活质量受损之间的关联并不强。
Background. Data are lacking on the prevalence of acne, its effects on quality of life (QOL) and the treatment usage among Chinese patients in late adolescence.Aim. To derive data about the prevalence and predictive factors of acne, the disability caused by acne and choice of treatment used by Chinese late adolescents in Hong Kong.Methods. This was a cross-sectional study of a random sample of 389 entrants in a university in Hong Kong, using the Global Acne Grading System (GAGS) to measure the clinical severity of acne and the Cardiff Acne Disability Index (CADI) to measure QOL.Results. The response rate was 99.3%. The prevalence of acne was of 81.5% (95% CI 77.6-85.4%) and coexisted with a high frequency of acne disability at a rate of 81.8% (95% CI 78.1-85.6%). Assessment of the clinical severity of acne did not correlate strongly with the effect on QOL (gamma(s) = 0.445, P < 0.001). Over the previous 6 months, 30.3% of subjects had used topical treatments, 3.9% had taken systemic conventional western drugs and 3.2% of the subjects had used traditional Chinese medicine. Multivariate logistic regression was used to explore the predictive factors for acne disability. Female gender (P = 0.002), higher GAGS score (P < 0.001), higher perceived stress (P = 0.01) and willingness to pay Hong Kong$15 000 (970) pound for a hypothetical permanent cure (P = 0.03) were positive predictors.Conclusions. Acne is prevalent in Hong Kong and has considerable psychological effects. The association between clinical severity and impaired QOL is not strong.