Pneumonia in gnotobiotic pigs produced by simultaneous inoculation of a swine adenovirus and mycoplasma hyopneumoniae
Pneumonia in gnotobiotic pigs produced by simultaneous inoculation of a swine adenovirus and mycoplasma hyopneumoniae
复制标题
同时接种猪腺病毒和猪肺炎支原体引起的无菌猪肺炎
DOI：
10.1136/vr.84.11.262
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发表时间：
1969
影响因子：
2.2
通讯作者：
P. Trexler
中科院分区：
文献类型：
--
作者：
L. Kasza;R. Hodges;A. O. Betts;P. Trexler
这两种药物产生了严重的肺炎，比单独使用任何一种药物都严重。肉眼可见病变包括心尖、心脏、隔叶前部和中间叶的双侧实变。显微镜下病变的特征为渗出性支气管肺炎合并间质性肺炎。增殖的隔细胞内可见核内包涵体。从猪中重新分离病毒和支原体。所有接种腺病毒的猪都对该病毒产生了强烈的抗体反应。
The two agents produced severe pneumonia, of greater severity than either agent alone. Macroscopic lesions consisted of bilateral consolidation in the apical, cardiac, anterior portion of diphragmatic and intermediate lobes. Microscopic lesions were characterized as an exudative bronchopneumonia in combination with interstitial pneumonia. Intranuclear inclusion bodies were demonstrated in the proliferating septal cells. Virus and mycoplasma were re-isolated from the pigs. All pigs inoculated with the adenovirus had a strong antibody response to this virus.