Relationship between activity levels and circadian blood pressure variations.
Relationship between activity levels and circadian blood pressure variations.
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活动水平与昼夜血压变化之间的关系。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
K. Tamura
中科院分区：
文献类型：
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作者：
I. Kohno;H. Ishii;T. Nakamura;K. Tamura
对17名健康的日本学生(男14名，女3名)，在手腕上安装活动水平监测仪(Actigraph)，48小时测量腕关节运动(加速度为0.01g或更高)。同时，在这些受试者身上安装了动态血压监测仪，每30分钟监测一次血压(BP)和心率(HR)。睡眠时间是根据活动水平计算出来的。Actigraph获得的睡眠时间与从日记中判断的睡眠时间相关。入睡时间的相关性要好于清醒时间。活动水平、心率和血压表现出相似的昼夜变化。白天活动(4500次/小时)和夜间睡眠(720次/小时)之间的活动水平有显著差异。余弦法测得活动水平的峰时相为235度，与BP、HR无显著差异。每小时的活动水平与相应时间的HR和BP相关。这些结果表明，血压受到活动水平的影响，即使这种节律在卧床休息时继续重复。
In 17 healthy Japanese students (14 males and 3 females) an ambulatory activity level monitoring instrument (Actigraph) was attached to the wrist for 48-hour measurement of wrist movement (with 0.01G or higher acceleration). At the same time, an ambulatory blood pressure monitoring apparatus was attached to these subjects to monitor blood pressure (BP) and heart rate (HR) every 30 minutes. Sleeping hours were calculated from the activity levels. The sleeping hours obtained by the Actigraph correlated with those judged from the diary. The correlation was better for the go-to-sleep time than for the awakening time. Activity level, HR and BP showed a similar circadian variation. Activity level differed significantly between the active daytime (4500 counts/hour) and during sleep at night (720 counts/hour). The acrophase of activity level, obtained by the cosinor method, was 235 degrees which did not significantly differ from that of BP and HR. Hourly activity levels correlated with HR and BP at corresponding hours. These results suggest that BP is affected by activity levels even if this rhythm continues to recur in bedrest.