Changes in protein metabolism in hemolymph and fat body of the silkworm, Bombyx mori (Lepidoptera: Bombycidae) in response to organophosphorus insecticides toxicity
Changes in protein metabolism in hemolymph and fat body of the silkworm, Bombyx mori (Lepidoptera: Bombycidae) in response to organophosphorus insecticides toxicity
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DOI：
10.1006/eesa.1996.1504
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发表时间：
1997-03-01
影响因子：
6.8
通讯作者：
Kumar, RPS
中科院分区：
文献类型：
--
作者：
Nath, BS;Suresh, A;Kumar, RPS
研究了致死和亚致死剂量杀螟硫磷和乙硫磷对五龄家蚕血淋巴和脂肪体蛋白质代谢的影响。总蛋白质含量表明，随着游离氨基酸积累的增加，蛋白质含量逐渐减少。同时，两种组织中的蛋白酶活性也增加。在所研究的组织中，丙氨酸转氨酶和天冬氨酸转氨酶的活性急剧增强，同时谷氨酸脱氢酶活性也随之升高。所有这些变化清楚地记录了氨基酸的严重蛋白水解和转氨作用的诱导。 (C) 1997 年学术出版社。
Changes in protein metabolism were studied in hemolymph and fat body of 5th instar silkworm Bombyx mori exposed to lethal and sublethal doses of fenitrothion and ethion. The total protein content indicated a depletion followed by a concomitant increase in accumulation of free amino acids. Concurrently, the activity of protease in both of the tissues was also increased. A sharp enhancement in the activities of alanine aminotransferase and aspartate aminotransferase paralleled the elevation of glutamate dehydrogenase activity in the tissues studied. All these changes clearly documented the induction of severe proteolysis and transamination of amino acids. (C) 1997 Academic Press.