PREVALENCE OF AGE-ASSOCIATED MEMORY IMPAIRMENT AND DEMENTIA IN A RURAL-COMMUNITY
PREVALENCE OF AGE-ASSOCIATED MEMORY IMPAIRMENT AND DEMENTIA IN A RURAL-COMMUNITY
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DOI：
10.1136/jnnp.56.9.973
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发表时间：
1993-09-01
影响因子：
11
通讯作者：
CLAVERIA, LE
中科院分区：
文献类型：
--
作者：
CORIA, F;DECASO, JAG;CLAVERIA, LE
为了准确估计与年龄相关的记忆障碍、痴呆和阿尔茨海默病的患病率，在西班牙塞哥维亚省的一个有1011名居民的农村社区Turegano进行了一项人口研究。该研究分为两个阶段：对40岁及以上的整个人群（503人）进行挨家挨户的调查，然后对疑似病例进行临床检查，以确定痴呆和认知障碍的阳性诊断和鉴别诊断。40岁及以上人群中与年龄相关的记忆障碍的患病率为3.6%，65岁及以上人群中为7.1%，而痴呆的患病率分别为2.6%和5- 2%。这两种临床疾病的患病率随着年龄的增长而增加。最常见的痴呆症临床类别是阿尔茨海默型痴呆症，占这两个年龄组的1.8%和3-8%。血管性痴呆的相应数字为0.4%和0.9%，继发性痴呆为0.4%和0.5%。阿尔茨海默病相关记忆障碍是一种年龄依赖性疾病，在老年人中患病率很高;其中一些患者可能代表阿尔茨海默病的早期阶段，这表明这种疾病的患病率可能高于先前的估计。
To obtain accurate estimates of the prevalence of age-associated memory impairment, dementia, and Alzheimer's disease, a population study was carried out in Turegano, a rural community of 1011 inhabitants in the Segovia province of Spain. The study was divided into two phases: a door to door survey of the entire population aged 40 years and over (503 persons), followed by a clinical examination of suspected cases for positive and differential diagnosis of dementia and cognitive impairment. The prevalence of age-associated memory impairment was 3.6% in individuals of 40 years and over and 7.1% in individuals of 65 years and over, whereas dementia was found in 2.6% and 5-2%, respectively. The prevalence rates of both clinical conditions increased with age. The most prevalent clinical category of dementia was dementia of Alzheimer type, which represented 1.8% and 3-8% of these two age groups. The corresponding figures for vascular dementia were 0.4% and 0.9% and for secondary dementia 0.4% and 0.5%. Age-associated memory impairment is an age-dependent disorder with a high prevalence among the elderly; some of these patients may represent an early stage of Alzheimer's disease, suggesting that the prevalence of this disorder may be higher than previously estimated.