Ecological studies of cancer incidence in an area interested by dumping waste sites in Campania (Italy)
Ecological studies of cancer incidence in an area interested by dumping waste sites in Campania (Italy)
复制标题
DOI：
10.4415/ann_11_02_10
复制
发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Fusco, Mario
中科院分区：
文献类型：
--
作者：
Fazzo, Lucia;Santis, Marco De;Fusco, Mario
在一个受到非法倾倒危险废物和焚烧管理不善废物的地区进行了癌症发病率调查。对于该地区由癌症登记处服务的 35 个城市，计算了城市标准化发病率 (SIR) 和分层贝叶斯估计量 (BIR)。此外，还对 10 种癌症类型进行了城市空间聚类和按城市废物相关暴露指数的泊松回归。某些癌症类型的市政府 SIR 有所增加。 BIR 证实两个城市的肝癌发病率有所增加。在肝脏、肺、白血病和软组织肉瘤中检测到具有统计学意义的簇。在回归分析中，睾丸癌与废物相关暴露指数呈显着趋势（RR = 1.18）。
Cancer incidence was investigated in an area which has been affected by the illegal practices of dumping hazardous waste and setting fire to mismanaged waste. For the 35 municipalities of this area that are served by a Cancer Registry, municipal standardized incidence ratios (SIR) and hierarchical Bayesian estimators (BIR) were computed. Moreover, municipal spatial clustering and a Poisson regression by municipality index of waste-related exposure were performed for 10 cancer types. increased municipality SIRs were found for some cancer types. The BIRs confirmed the increases for liver cancer in two municipalities. Statistically significant clusters were detected for liver, lung, leukaemia and soft tissue sarcomas. In the regression analysis, testis cancer showed significant trend with the index of waste-related exposure (RR = 1.18).