A MOLECULAR SWITCH FOR THE CONSOLIDATION OF LONG-TERM-MEMORY - CAMP-INDUCIBLE GENE-EXPRESSION

A MOLECULAR SWITCH FOR THE CONSOLIDATION OF LONG-TERM-MEMORY - CAMP-INDUCIBLE GENE-EXPRESSION
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DOI:
10.1111/j.1749-6632.1995.tb24833.x
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发表时间:
1995-01-01
期刊:
DNA: THE DOUBLE HELIX
影响因子:
--
通讯作者:
KANDEL, ER
KANDEL, ER
中科院分区:
其他
文献类型:
--
作者:
ALBERINI, CM;GHIRARDI, M;KANDEL, ER

文献摘要

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As this symposium illustrates, molecular genetics has brought about a dra-matic unification within the biological sciences. The ability to sequence genes, and to infer the amino acid sequence of the proteins they encode, has revealed unanticipated relationships between proteins encountered in different contexts. As a result, there is now a general blueprint for cell function that provides a common conceptual framework for several, previously unrelated, disciplines: genetics, biochemistry, immunology, development, cell biology, and neurobiology. A parallel and potentially equally profound unification is occurring between neural science, the science of the brain, and cognitive psychology, the science of the mind. The ability to study the neuronal basis of mental function is providing a new impetus for examining cognitive processes such as perception, action, language, learning, and memory. To what degree can these two independent and disparate strands be brought together? Can molecular biology enlighten the study of mental processes? In this brief review we outline the possibility of a molecular bw&y ofcoflition, using as examples several simple forms of memory and learning in invertebrates and vertebrates.