Urinary Acid Mucopolysaccharide Inhibitors of Calcium Oxalate Crystallisation

Urinary Acid Mucopolysaccharide Inhibitors of Calcium Oxalate Crystallisation
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尿酸性粘多糖草酸钙结晶抑制剂

DOI:
10.1007/978-1-4613-4295-3_42
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发表时间:
1976
期刊:
Investigative urology
影响因子:
--
通讯作者:
M. Peacock
M. Peacock
中科院分区:
--
文献类型:
--
作者:
W. Robertson;F. Knowles;M. Peacock

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Studies by a number of workers have shown that normal urine contains at least two inhibitors of the growth and aggregation of calcium oxalate crystals in vitro (1–5). Of these, a low molecular weight material, possibly pyrophosphate, accounts for about 10–15% of the total inhibitory activity of urine (4,5), the remaining activity being attributed to a high molecular weight component thought to be in the acid mucopolysaccharide (AMPS) fraction (4). The present paper examines the evidence that the main inhibitor of calcium oxalate crystallisation is an acid mucopolysaccharide.